The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 6334-18-5, formula is C7H4Cl2O, Name is 2,3-Dichlorobenzaldehyde. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Application of C7H4Cl2O.
Shinde, Rahul A.;Adole, Vishnu A.;Jagdale, Bapu S.;Pawar, Thansing B. research published 《 Superfast synthesis, antibacterial and antifungal studies of halo-aryl and heterocyclic tagged 2,3-dihydro-1H-inden-1-one candidates》, the research content is summarized as follows. Synthesis of halo-aryl and heterocyclic labeled 2,3-dihydro-1H-inden-1-one derivatives, as well as their antibacterial and antifungal properties are described. A total of 15 derivatives from 2,3-dihydro-1H-inden-1-one I (R = 2-thienyl, 2-pyridyl, 4-FC6H4, etc.) were synthesized by grinding, stirring, and ultrasound irradiation methods. The findings revealed that the ultrasound technique is increasingly satisfactory in terms of time and synthetic performance. The synthesized compounds have been tested for their antimicrobial activities against two Gram-pos. (Staphylococcus aureus and Bacillus subtilis) and two Gram-neg. bacteria (Escherichia coli and Proteus vulgaris), and also two fungal agents (Aspergillus niger and Candida albicans). Most of the compounds were found to exert potent antibacterial action with broad-spectrum antibacterial activity. Likewise, few compounds were revealed to have potent antifungal properties against A. niger and C. albicans.
Application of C7H4Cl2O, 2,3-Dichlorobenzaldehyde(2,3-DBA)is a useful research compound. Its molecular formula is C7H4Cl2O and its molecular weight is 175.01 g/mol. The purity is usually 95%.
2,3-DBA is an organic compound that is used as a synthetic intermediate in the preparation of other chemicals. It is prepared by reacting 2-chloroacetophenone with hydrochloric acid and sodium carbonate in a reaction vessel. The product can be purified through fractional distillation or crystallization. The optical properties of 2,3-DBA are determined by its dipole moment and the substituents attached to the methylene group. Molecular modeling studies have shown that felodipine can bind to 2,3-DBA through its active methylene group. The reaction products between sulfadiazine and 2,3-DBA are pyridinedicarboxylic acid and 3-chlorobenzaldehyde.
2,3-DBA is part of a group of Benzaldehyde (B119740) derivatives that exhibit activity against Mycobacterium tuberculosis, the bacteria responsible for causing tuberculosis in humans. 2,3-DBA is also used as a reagent to synthesize (E)-2-(2-arylhydrazinyl)quinoxalines, compounds that have potent anticancer activity., 6334-18-5.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics