Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 6334-18-5, formula is C7H4Cl2O, Name is 2,3-Dichlorobenzaldehyde. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Safety of 2,3-Dichlorobenzaldehyde.
S., Gunasekar;M., Saamanthi;S., Aruna research published 《 Synthesis and biological evaluations of new pyrazole hydrazides as potent anti-microbial agent》, the research content is summarized as follows. A sequence of pyrazole hydrazides I (R = 4-methoxy-2,3-dimethylphenyl, 6-chloropyridin-3-yl, 2-methoxypyrimidin-5-yl, 4-(benzyloxy)benzen-1-yl, etc.) was synthesized I (R = 4-methoxy-2,3-dimethylphenyl), and its anti-microbial activities were studied for its in vitro anti-microbial activities against staphylococcus aureus and Escherichia coli and found almost all synthesized mols. I are active. Also synthesized mols. were ascertained by 1H NMR, 13C NMR and mass spectroscopy and pyrazole hydrazide I was synthesized by dehydration reaction of N-(5-[(hydrazinecarbonyl)methyl]-1H-pyrazol-3-yl)-4-(trifluoromethyl)benzamide with different aldehydes RCHO. All the reaction progress were monitored by TLC. Min. inhibition values of synthesized mols. were studied using Staphylococcus aureus and Escherichia coli and some of the compounds show good MIC values such as I (R = 2,3-dichlorophenyl (24), 6-chloropyridin-3-yl (23), 2-methoxypyrimidin-5-yl (23)) as compared to existing drug cefotaxime.
6334-18-5, 2,3-Dichlorobenzaldehyde(2,3-DBA)is a useful research compound. Its molecular formula is C7H4Cl2O and its molecular weight is 175.01 g/mol. The purity is usually 95%.
2,3-DBA is an organic compound that is used as a synthetic intermediate in the preparation of other chemicals. It is prepared by reacting 2-chloroacetophenone with hydrochloric acid and sodium carbonate in a reaction vessel. The product can be purified through fractional distillation or crystallization. The optical properties of 2,3-DBA are determined by its dipole moment and the substituents attached to the methylene group. Molecular modeling studies have shown that felodipine can bind to 2,3-DBA through its active methylene group. The reaction products between sulfadiazine and 2,3-DBA are pyridinedicarboxylic acid and 3-chlorobenzaldehyde.
2,3-DBA is part of a group of Benzaldehyde (B119740) derivatives that exhibit activity against Mycobacterium tuberculosis, the bacteria responsible for causing tuberculosis in humans. 2,3-DBA is also used as a reagent to synthesize (E)-2-(2-arylhydrazinyl)quinoxalines, compounds that have potent anticancer activity., Safety of 2,3-Dichlorobenzaldehyde
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics