The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 104-86-9, formula is C7H8ClN, Name is (4-Chlorophenyl)methanamine. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Safety of (4-Chlorophenyl)methanamine.
Palani, Pushbaraj;Chithiraivel, Vinoth;Chandru Senadi, Gopal research published 《 Visible-Light Photocatalyzed Oxidative Coupling of Benzylamines with Nucleophiles: Synthesis of 2-Aryl benzothiazoles and α,β-Unsaturated esters》, the research content is summarized as follows. The oxidation of amines is considered as one of the important way for producing key synthetic intermediates such as aldehydes, ketones, imines, oximes, amides, nitriles and nitro compounds using suitable reaction conditions. Recently, the utilization of light as an energy source in organic synthesis have gained significant interest and has delivered the key development to the visible-light photoredox catalysis. Herein, authors developed the oxidation of benzylamine derivatives using rose bengal as a photocatalyst under visible-light irradiation followed by trapping with nucleophiles like 2-aminothiophenol and dimethylmalonate for the construction of 2-aryl benzothiazoles I (R = H, 4-t-Bu, 4-OMe, 4-Cl, 4-F) and α,β-unsaturated esters II (R = H, 4-OMe, 4-Cl, 4-F, 2-Me). The proof of concept has been established by synthesizing five benzothiazole derivatives and five α,β-unsaturated esters. The key features of this method are metal-free, no external oxidants such as peroxide and ambient reaction temperature
Safety of (4-Chlorophenyl)methanamine, 4-Chlorobenzylamine is a useful research compound. Its molecular formula is C7H8ClN and its molecular weight is 141.6 g/mol. The purity is usually 95%.
4-Chlorobenzylamine is a reactant in the environmentally friendly synthesis of pyrroles.
4-Chlorobenzylamine is a chemical that is used as an intermediate in the synthesis of other compounds. It has low bioavailability, which may be due to its reactive site. The chemical can be characterized using nmr spectra and potent inhibitory activity. 4-Chlorobenzylamine has been found to react with nitrogen atoms, and this reaction is highly acidic. FT-IR spectroscopy can also be used to characterize this compound. Intermolecular hydrogen bonding and hydroxyl group are two of the major interactions of 4-chlorobenzylamine with other molecules. This chemical reacts with serine protease, glyoxal, and other substances in a manner that depends on the molecule’s structure., 104-86-9.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics