Liddle, John team published research in Bioorganic & Medicinal Chemistry Letters in 2021 | 3900-89-8

Recommanded Product: (2-Chlorophenyl)boronic acid, 2-Chlorophenylboronic acid is a useful research compound. Its molecular formula is C6H6BClO2 and its molecular weight is 156.38 g/mol. The purity is usually 95%.
2-Chlorophenylboronic acid used in the preparation of imidazo[1,2-a]pyridine amides which has tuberculostatic activity.
2-Chlorophenylboronic acid is a diphenyl ether that can be used as a building block for the synthesis of benzodiazepine receptor ligands. It has been shown to be an efficient nucleophile, leading to the formation of carbonyl groups in the presence of halides. 2-Chlorophenylboronic acid has also been shown to inhibit p38 kinase activity and may be useful for anticancer therapy., 3900-89-8.

Chloride substituents modify the physical properties of organic compounds in several ways. 3900-89-8, formula is C6H6BClO2, Name is (2-Chlorophenyl)boronic acid. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Recommanded Product: (2-Chlorophenyl)boronic acid.

Liddle, John;Pearce, Andrew C.;Arico-Muendel, Christopher;Belyanskaya, Svetlana;Brewster, Andrew;Brown, Murray;Chung, Chun-wa;Denis, Alexis;Dodic, Nerina;Dossang, Anthony;Eddershaw, Peter;Klimaszewska, Diana;Haq, Imran;Holmes, Duncan S.;Jagger, Alistair;Jakhria, Toral;Jigorel, Emilie;Lind, Ken;Messer, Jeff;Neu, Margaret;Olszewski, Allison;Ronzoni, Riccardo;Rowedder, James;Rudiger, Martin;Skinner, Steve;Smith, Kathrine J.;Trottet, Lionel;Uings, Iain;Zhu, Zhengrong;Irving, James A.;Lomas, David A. research published 《 The development of highly potent and selective small molecule correctors of Z α1-antitrypsin misfolding》, the research content is summarized as follows. α1-Antitrypsin deficiency is characterized by the misfolding and intracellular polymerization of mutant α1-antitrypsin protein within the endoplasmic reticulum (ER) of hepatocytes. Small mols. that bind and stabilize Z α1-antitrypsin were identified via a DNA-encoded library screen. A subsequent structure-based optimization led to a series of highly potent, selective and cellular active α1-antitrypsin correctors, e.g., I.

Recommanded Product: (2-Chlorophenyl)boronic acid, 2-Chlorophenylboronic acid is a useful research compound. Its molecular formula is C6H6BClO2 and its molecular weight is 156.38 g/mol. The purity is usually 95%.
2-Chlorophenylboronic acid used in the preparation of imidazo[1,2-a]pyridine amides which has tuberculostatic activity.
2-Chlorophenylboronic acid is a diphenyl ether that can be used as a building block for the synthesis of benzodiazepine receptor ligands. It has been shown to be an efficient nucleophile, leading to the formation of carbonyl groups in the presence of halides. 2-Chlorophenylboronic acid has also been shown to inhibit p38 kinase activity and may be useful for anticancer therapy., 3900-89-8.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics