Jose, Arathy team published research in ChemMedChem in 2022 | 1878-65-5

Reference of 1878-65-5, 3-Chlorophenylacetic acid is a useful research compound. Its molecular formula is C8H7ClO2 and its molecular weight is 170.59 g/mol. The purity is usually 95%.
3-Chlorophenyl acetic acid is a compound that has resonance mass of 269. The compound reacts with HBr and water to produce 3-chlorobenzene, carbon dioxide and hydrogen chloride. A reaction product of this chemical is covid-19 pandemic (a type of drug)., 1878-65-5.

Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 1878-65-5, formula is C8H7ClO2, Name is 3-Chlorophenylacetic acid. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Reference of 1878-65-5.

Jose, Arathy;Guest, Daniel;LeGay, Remi;Tizzard, Graham J.;Coles, Simon J.;Derveni, Mariliza;Wright, Edward;Marrison, Lester;Lee, Alpha A.;Morris, Aaron;Robinson, Matt;von Delft, Frank;Fearon, Daren;Koekemoer, Lizbe;Matviuk, Tetiana;Aimon, Anthony;Schofield, Christopher J.;Malla, Tika R.;London, Nir;Greenland, Barnaby W.;Bagley, Mark C.;Spencer, John;The Covid Moonshot Consortium research published �Expanding the Repertoire of Low-Molecular-Weight Pentafluorosulfanyl-Substituted Scaffolds� the research content is summarized as follows. The pentafluorosulfanyl (-SF5) functional group is of increasing interest as a bioisostere in medicinal chem. A library of SF5-containing compounds, including amide, isoxazole, and oxindole derivatives, was synthesized using a range of solution-based and solventless methods, including microwave and ball-mill techniques. The library was tested against targets including human dihydroorotate dehydrogenase (HDHODH). A subsequent focused approach led to synthesis of analogs of the clin. used disease modifying anti-rheumatic drugs (DMARDs), Teriflunomide and Leflunomide, considered for potential COVID-19 use, where SF5 bioisostere deployment led to improved inhibition of HDHODH compared with the parent drugs. The results demonstrate the utility of the SF5 group in medicinal chem.

Reference of 1878-65-5, 3-Chlorophenylacetic acid is a useful research compound. Its molecular formula is C8H7ClO2 and its molecular weight is 170.59 g/mol. The purity is usually 95%.
3-Chlorophenyl acetic acid is a compound that has resonance mass of 269. The compound reacts with HBr and water to produce 3-chlorobenzene, carbon dioxide and hydrogen chloride. A reaction product of this chemical is covid-19 pandemic (a type of drug)., 1878-65-5.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics