The author of 《Pd/Xiang-Phos-catalyzed enantioselective intermolecular carboheterofunctionalization under mild conditions》 were Tao, Mengna; Tu, Youshao; Liu, Yu; Wu, Haihong; Liu, Lu; Zhang, Junliang. And the article was published in Chemical Science in 2020. Synthetic Route of C18H24Cl2N2Pd2 The author mentioned the following in the article:
A mild and practical Pd/Xiang-Phos-catalyzed enantioselective intermol. carboheterofunctionalization reaction of 2,3-dihydrofurans I (R = H, 4-MeC6H4, quinolin-2-yl, benzofuran-5-yl, 4-MeO2CC6H4) was developed, leading to various optically active fused furoindolines II (R1 = H, F, Me, R2 = H, Cl, Me, CF3, etc., R3 = H, F, MeO2C, Me, etc., R4 = H, F, R1R2 = -N=CHCH=N-, PG = Ts, SO2Ph), III (R = 4-MeC6H4, 4-MeO2CC6H4, benzofuran-5-yl), and tetrahydrofurobenzofurans IV (R5 = H, F, Me, OMe, R6 = H, F, Me, R7 = H, F, OMe) and V (R = 4-MeC6H4, 4-MeO2C6H4, benzofuran-5-yl, quinolin-2-yl, H). The key to this transformation is employing two newly modified N-Me-Xiang-Phos ligands (S,RS)-VI (Ar = Ph, 3,5-(tert-Bu)2-4-MeOC6H2) as chiral ligands under mild conditions. Moreover, this synthetic methodol. can be efficiently applied to a variety of complex polysubstituted heterocycles with high chemo-, regio-, and enantio-selectivities via introducing diverse substituents on furan rings, which were hard to access by other routes. After reading the article, we found that the author used Di-μ-chlorobis[2-[(dimethylamino)methyl]phenyl-C,N]dipalladium(II)(cas: 18987-59-2Synthetic Route of C18H24Cl2N2Pd2)
Di-μ-chlorobis[2-[(dimethylamino)methyl]phenyl-C,N]dipalladium(II)(cas: 18987-59-2) belongs to organochlorine compounds. Many organochlorine compounds have been isolated from natural sources ranging from bacteria to humans. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Synthetic Route of C18H24Cl2N2Pd2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics