《Perfluoroalkylation of Thiosulfonates: Synthesis of Perfluoroalkyl Sulfides》 was written by Luo, Ziwei; Yang, Xinkan; Tsui, Gavin Chit. Recommanded Product: 16629-19-9 And the article was included in Organic Letters in 2020. The article conveys some information:
A practical synthesis of perfluoroalkyl sulfides is described. The method employs stable and readily accessible thiosulfonates as new electrophiles with com. nucleophilic perfluoroalkylating reagents. The mild reaction conditions allow access to a wide variety of both aryl- and alkyl-substituted perfluoroalkyl sulfides amenable to pharmaceutical development. Furthermore, the reaction operation is straightforward, odorless, does not produce toxic wastes, and, therefore should appeal to practitioners in industrial-scale productions. In the experiment, the researchers used Thiophene-2-sulfonyl chloride(cas: 16629-19-9Recommanded Product: 16629-19-9)
Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Recommanded Product: 16629-19-9
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics