COA of Formula: C6H4Cl2O2SIn 2022 ,《Electrochemically-promoted synthesis of benzo[b]thiophene-1,1-dioxides via strained quaternary spirocyclization》 was published in Chemical Science. The article was written by Li, Ruitao; Yuan, Dafu; Ping, Mengqi; Zhu, Yuyi; Ni, Shaofei; Li, Ming; Wen, Lirong; Zhang, Lin-Bao. The article contains the following contents:
An approach for the synthesis of benzothiophene motifs under electrochem. conditions by the reaction of sulfonhydrazides with internal alkynes was reported. Upon the formation of a quaternary spirocyclization intermediate by the selective ipso-addition instead of an ortho-attack, the S-migration process was rationalized to lead to the products. Computational studies revealed the selectivity and the compatibility of drug mols. showcased the potential application of the protocols. In the experiment, the researchers used 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2COA of Formula: C6H4Cl2O2S)
4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.COA of Formula: C6H4Cl2O2S
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics