Recommanded Product: 620-20-2On November 30, 2019 ,《An improved method for the synthesis of phenylacetic acid derivatives via carbonylation》 appeared in Journal of Chemical Research. The author of the article were Li, He; Zhang, Yijun; Liu, Dinghua; Liu, Xiaoqin. The article conveys some information:
A series of phenylacetic acid derivatives RCH2CO2H [R = 2-ClC6H4, 4-MeC6H4, 2,4-Cl2C6H3, etc.] was synthesized via bistriphenylphosphine palladium dichloride catalyzed carbonylation reaction of benzyl chloride derivatives in presence of tetraethylammonium chloride and sodium hydroxide as reagents and xylene as solvent at 80°C under a CO atm. 2,4-Dichlorophenylacetic acid was obtained in a maximum yield of 95% from 2,4-dichlorobenzyl chloride using the same reaction system. In the experimental materials used by the author, we found 3-Chlorobenzylchloride(cas: 620-20-2Recommanded Product: 620-20-2)
3-Chlorobenzylchloride(cas: 620-20-2) has been used in the reaction of 3-methoxybenzyl chloride and ethyl 4-bromobenzoate in pure water, using zinc dust and a Pd catalyst.Recommanded Product: 620-20-2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics