El Ashry, E. S. H.; Abdel-Rahman, A. A.-H.; Rashed, N.; Rasheed, H. A. published their research in Pharmazie on December 31 ,1999. The article was titled 《Homoacyclovir analogs of unnatural bases and their activity against hepatitis B virus》.HPLC of Formula: 14258-40-3 The article contains the following contents:
The ambident nucleophilic nature of the sodium salts of 2(1H)-quinoxalinone and 2-phenylphthalazinedione has been realized from their alkylation with 2-(2-chloroethoxy)ethyl acetate to afford N- and O-alkylated derivatives, e.g., I and II. Four addnl. N-alkylated heterocycles were similarly prepared from unnatural bases. Treatment of the alkylated derivatives with methanolic ammonia solution (1:1) at room temperature gave the hydroxyalkyl derivatives The site of alkylation was deduced from the spectral characteristics of the products. The activity of several compounds against hepatitis B virus in HepG2 cells has been tested. Some of the compounds showed high viral replication inhibition with low cytotoxicity. In the experiment, the researchers used many compounds, for example, 2-(2-Chloroethoxy)ethyl acetate(cas: 14258-40-3HPLC of Formula: 14258-40-3)
2-(2-Chloroethoxy)ethyl acetate(cas: 14258-40-3) belongs to aliphatic hydrocarbons. Aliphatic hydrocarbons belong to the most abundant fraction in crude oil. Aliphatics molecules are linear or branched open-chain structures such as n-alkanes, isoalkanes, cycloalkanes (naphthenes), terpenes and steranes.HPLC of Formula: 14258-40-3
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics