Di Mola, Antonia’s team published research in ChemistrySelect in 2019 | CAS: 622-95-7

1-(Bromomethyl)-4-chlorobenzene(cas: 622-95-7) is a useful reagent for the preparation of panicinotam derivatives for use as anti-inflammatory agents or immunomodulators.COA of Formula: C7H6BrCl It can be synthesized by reacting 4-chlorobenzyl alcohol with bromodimethylsulfonium bromide (BDMS) It can also be synthesized by refluxing a mixture of 4-chlorobenzaldehyde, chlorotrimethylsilane, 1,1,3,3-tetramethyldisiloxane and lithium bromide.

In 2019,ChemistrySelect included an article by Di Mola, Antonia; Macchia, Antonio; Tedesco, Consiglia; Pierri, Giovanni; Palombi, Laura; Filosa, Rosanna; Massa, Antonio. COA of Formula: C7H6BrCl. The article was titled 《Synthetic Strategies and Cascade Reactions of 2-Cyanobenzophenones for the Access to Diverse 3,3-Disubstituted Isoindolinones and 3-Aryl-3-Hydroxyisoindolinones》. The information in the text is summarized as follows:

New methodologies for the synthesis of the challenging ketones 2-cyanobenzophenones, based on Suzuki-Miyaura type cross-coupling reactions and very mild oxidation of 2-benzylbenzonitriles. The investigation of the reactivity of the obtained ketones highlighted a very good electrophilicity in the presence of mild carbon- and hetero-nucleophiles, allowing the synthesis of 3,3-disubstituted isoindolin-1-ones. All the developed methodologies were highly efficient and tolerated combinations of functional groups present on both the aromatic rings. In the part of experimental materials, we found many familiar compounds, such as 1-(Bromomethyl)-4-chlorobenzene(cas: 622-95-7COA of Formula: C7H6BrCl)

1-(Bromomethyl)-4-chlorobenzene(cas: 622-95-7) is a useful reagent for the preparation of panicinotam derivatives for use as anti-inflammatory agents or immunomodulators.COA of Formula: C7H6BrCl It can be synthesized by reacting 4-chlorobenzyl alcohol with bromodimethylsulfonium bromide (BDMS) It can also be synthesized by refluxing a mixture of 4-chlorobenzaldehyde, chlorotrimethylsilane, 1,1,3,3-tetramethyldisiloxane and lithium bromide.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics