Yuan, Pan-Feng; Huang, Tao; He, Jian; Huang, Xie-Tian; Jin, Xiao-Ling; Sun, Chunlin; Wu, Li-Zhu; Liu, Qiang published an article in 2021. The article was titled 《Controllable Z/E-selective synthesis of α-amino-ketoximes from N-nitrososulfonamides and aryl alkenes under neutral conditions》, and you may find the article in Organic Chemistry Frontiers.COA of Formula: C6H4Cl2O2S The information in the text is summarized as follows:
Design of a photosensitization strategy to generate the unique triplet state reactivity of N-nitrososulfoximides, specifically N-methyl-N-nitroso-p-toluenesulfonamides (NANS1) and the subsequent installation of both N-centered sulfonamidyl radical and nitric oxide functionalities into aryl alkene feedstocks were reported, which was mild and completely atom economical, exhibited broad functional group tolerance and occur readily under neutral conditions. Furthermore, this newly developed methodol. was also compatible with both terminal and internal 1,3-dienes to afford solely 1,2-amidoximation products in a remarkable regio- and Z/E-selective manner. Compared with traditional methods that are based on the steric hindrance of the substrates to control the reaction selectivity, both the (E)- and (Z)-isomers of α-amino-ketoximes was obtained selectively by the switch of sensitizers in this protocol. The key photophys. properties of NANS1 and DFT calculations were investigated in detail, providing the fact that the reaction proceeded through a sensitized triplet energy transfer pathway. In the experimental materials used by the author, we found 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2COA of Formula: C6H4Cl2O2S)
4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.COA of Formula: C6H4Cl2O2S
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics