Electric Literature of C6H6BFO2In 2020 ,《Palladium-Catalyzed Cascade Reactions of δ-Ketonitriles with Arylboronic Acids: Synthesis of Pyridines》 appeared in ACS Combinatorial Science. The author of the article were Yao, Xinrong; Qi, Linjun; Li, Renhao; Zhen, Qianqian; Liu, Jichao; Zhao, Zhiwei; Shao, Yinlin; Hu, Maolin; Chen, Jiuxi. The article conveys some information:
This study presents the first example of the Pd-catalyzed cascade reactions of 5-oxohexanenitrile with arylboronic acids, affording important synthon 2-methylpyridines that can be further translated through C(sp3)-H functionalization to construct pyridine derivatives Furthermore, this chem. allows 5-oxo-5-arylpentanenitrile to react with arylboronic acids to provide unsym. 2,6-diarylpyridines. This protocol paves the way for the practical and atom economical syntheses of valuable pyridines with broad functional groups in moderate to excellent yields under mild conditions. In the experiment, the researchers used many compounds, for example, (3-Fluorophenyl)boronic acid(cas: 768-35-4Electric Literature of C6H6BFO2)
(3-Fluorophenyl)boronic acid(cas: 768-35-4) can be used to make novel liquid crystalline fluorobiphenylcyclohexenes and difluoroterphenyls by palladium-catalyzed cross-couplings also used in the synthesis of o-phenylphenols as potent leukotriene B4 receptor agonists.Electric Literature of C6H6BFO2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics