SDS of cas: 79349-53-4On May 30, 1993, Okita, Takaaki; Imae, Kiyoto; Hasegawa, Toshifumi; Iimura, Seiji; Masuyoshi, Shinji; Kamachi, Hajime; Kamei, Hideo published an article in Journal of Antibiotics. The article was 《Synthesis and antibacterial activity of cephalosporins having a catechol in the C3 side chain》. The article mentions the following:
Cephalosporins I [R = H, Me, CMe2CO2H, R1 = (E)-CH:CHCH2O2CC6H3(OH)2-3,4, O2CC6H3(OH)2-3,4; R = Me, R1 = O2CCH2C6H3(OH)2-3,4] were prepared I [ R = CMe2CO2H, R1 = (E)-CH:CHCH2O2CC6H3(OH)2-3,4, O2CC6H3(OH)2-3,4] showed excellent activity against Gram-neg. bacteria including ceftazidime-resistant Escherichia coli, Pseudomonas aeruginosa, Xanthomonas maltophilia and Pseudomonas cepacia. In the experiment, the researchers used many compounds, for example, (6R,7R)-Benzhydryl 7-amino-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride(cas: 79349-53-4SDS of cas: 79349-53-4)
(6R,7R)-Benzhydryl 7-amino-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride(cas:79349-53-4) is one of azetidine.Azetidines (azacyclobutanes) constitute a well-known class of heterocyclic compounds. Azetidine scaffold has been discovered in several natural products.SDS of cas: 79349-53-4 Several pharmacologically important synthetic compounds also contain azetidine ring. Because of inherent ring strain, the synthesis of azetidines is a challenging endeavor.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics