《Arylsulfochlorination of β-aminopropioamidoximes giving 2-aminospiropyrazolylmorpholine-ammonium arylsulfonates》 was published in Russian Chemical Bulletin in 2020. These research results belong to Kayukova, L. A.; Praliyev, K. D.; Myrzabek, A. B.; Kainarbayeva, Zh. N.. Synthetic Route of C6H4Cl2O2S The article mentions the following:
The reaction of P-(morpholin-1-yl)propioamidoxime with aromatic sulfonyl chlorides (p-XC6H4SO2Cl; X = CH3O, CH3, H, Br, Cl, NO2) in chloroform in the presence of triethylamine does not produce expected O-arylsulfonyl-β-(morpholin-1-yl)propioamidoximes; instead, this reaction affords isomers of the latter compounds, 2-amino-8-oxa-l,5-diazaspiro[4.5]dec-1-ene-5-ammonium arylsulfonates. The structures of the reaction products were established by physicochem. methods, spectroscopy, and X-ray diffraction. In the experiment, the researchers used 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Synthetic Route of C6H4Cl2O2S)
4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Synthetic Route of C6H4Cl2O2S
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics