《Divergent Palladium-Catalyzed Tandem Reaction of Cyanomethyl Benzoates with Arylboronic Acids: Synthesis of Oxazoles and Isocoumarins》 was written by Dai, Ling; Yu, Shuling; Xiong, Wenzhang; Chen, Zhongyan; Xu, Tong; Shao, Yinlin; Chen, Jiuxi. Computed Properties of C6H6BFO2 And the article was included in Advanced Synthesis & Catalysis in 2020. The article conveys some information:
A palladium-catalyzed tandem reaction of cyanomethyl benzoates with arylboronic acids has been achieved. Substitution at the 2-position of cyanomethyl benzoates was found to be crucial for the selective synthesis of oxazoles and isocoumarins. Cyanomethyl benzoates afforded 2,4-diaryloxazoles as products, while 2-benzoyl-substituted cyanomethyl benzoates delivered 3-benzoyl-4-aryl-isocoumarins selectively. Furthermore, a possible mechanism for the selective reaction of cyanomethyl benzoates with arylboronic acids was discussed. In addition to this study using (3-Fluorophenyl)boronic acid, there are many other studies that have used (3-Fluorophenyl)boronic acid(cas: 768-35-4Computed Properties of C6H6BFO2) was used in this study.
(3-Fluorophenyl)boronic acid(cas: 768-35-4) can be used to make novel liquid crystalline fluorobiphenylcyclohexenes and difluoroterphenyls by palladium-catalyzed cross-couplings also used in the synthesis of o-phenylphenols as potent leukotriene B4 receptor agonists.Computed Properties of C6H6BFO2
Referemce:
Chloride – Wikipedia,
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