In 2022,Che, Zhiping; Li, Yuanhao; Guo, Xiaolong; He, Jiaxuan; Zhang, Song; Zhu, Lina; Liu, Yibo; Wei, Ruxue; Yang, Yingjun; Huang, Xiaobo; Liu, Shengming; Chen, Genqiang; Tian, Yuee published an article in Chemistry & Biodiversity. The title of the article was 《Synthesis and Anti-Oomycete Activity of Sulfonate Derivatives of Fenjuntong》.Related Products of 16629-19-9 The author mentioned the following in the article:
In order to discover highly active fungicides, sixteen novel sulfonate derivatives of Fenjuntong were synthesized by structural modification of 2′-hydroxybutyrophenone, and their anti-oomycete activity against Phytophthora capsici Leonian was determined in this study. Among all tested compounds, compound I displayed more significant anti-oomycete activity than the precursor Fenjuntong against P. capsici, and the EC50 values of I and Fenjuntong were 84.50 and 517.25 mg/L, resp. By comparing the anti-oomycete activity of compounds the following conclusions were drawn: (1) Hydroxy group is well tolerated, and sulfonylation of hydroxy group enhances its anti-oomycete activity. (2) The proper length of the ketone carbonyl chain is very important for their anti-oomycete activity. (3) The presence of a site methoxy group in the structural skeleton is closely related to the anti-oomycete activity. These important results will pave the way for further modification of Fenjuntong to develop potential new fungicides. The results came from multiple reactions, including the reaction of Thiophene-2-sulfonyl chloride(cas: 16629-19-9Related Products of 16629-19-9)
Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Related Products of 16629-19-9
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics