Quality Control of Di-μ-chlorobis[2-[(dimethylamino)methyl]phenyl-C,N]dipalladium(II)On May 13, 2019 ,《Synthesis and Catalytic Applications of Heterobimetallic Carbene Complexes Obtained via Sequential Metalation of Two Bisazolium Salts》 appeared in Organometallics. The author of the article were Boehmer, Maximilian; Guisado-Barrios, Gregorio; Kampert, Florian; Roelfes, Florian; Tan, Tristan Tsai Yuan; Peris, Eduardo; Hahn, F. Ekkehardt. The article conveys some information:
A simple sequential metalation approach starting from the imidazolium/benzimidazolium salt 4(I)2 yielded the heterobimetallic RhIII/M (M = PdII, IrI, AuI, RuII) complexes [6]-[9]. Alternatively, a sym. 1,3-imidazolium substituted benzene was used for the preparation of the heterobimetallic M’/PdII (M’ = RhIII, IrIII) complexes [12] and [13]. The versatile stepwise approach used for the preparation of complexes [6]-[9] involved the deprotonation reaction of the bisazolium salt 4(I)2 in the presence of [RhCp*(Cl)2]2 to afford the monometallic complex [5]I featuring a chelating coordinated bidentate CNHC^Cphenyl ligand. Complex [5]I was reacted with Ag2O to give a nonisolated RhIII/AgI complex which in a subsequent transmetalation reaction yielded the heterobimetallic RhIII/M bis-NHC complexes (M = PdII [6], IrI [7], AuI [8], RuII [9]). Similarly, heterobimetallic M’/PdII bis-NHC complexes [12] (M’ = RhIII) and [13] (M’ = IrIII) have been prepared from a sym. bisazolium salt by generating first the monometallic M’ complexes followed by a transmetalation reaction of the in situ generated M’/AgI complexes with [Pd(dmba)(μ-Cl)]2. The RhIII/PdII complexes [6] and [12] and the IrIII/PdII complex [13] were used as catalysts for two orthogonal tandem reactions, namely, the Suzuki-Miyaura coupling/transfer hydrogenation and the Suzuki-Miyaura-coupling/α-alkylation of ketones. The catalytic activity of the heterobimetallic complexes was compared to mixtures of the related monometallic analogs [14]-[17], with the heterobimetallic complexes generally showing a higher catalytic activity. In addition, nBuOH was found to play a dual role as an alkylating and reducing agent in the Suzuki-Miyaura coupling/α-alkylation of ketones. After reading the article, we found that the author used Di-μ-chlorobis[2-[(dimethylamino)methyl]phenyl-C,N]dipalladium(II)(cas: 18987-59-2Quality Control of Di-μ-chlorobis[2-[(dimethylamino)methyl]phenyl-C,N]dipalladium(II))
Di-μ-chlorobis[2-[(dimethylamino)methyl]phenyl-C,N]dipalladium(II)(cas: 18987-59-2) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Quality Control of Di-μ-chlorobis[2-[(dimethylamino)methyl]phenyl-C,N]dipalladium(II)
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Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics