Blanco, Christian O.’s team published research in Organometallics in 2021 | CAS: 172222-30-9

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is a ruthenium-based olefin metathesis catalyst. It is useful for olefin cross metathesis (CM) and ring closing metathesis (RCM) of terminal olefins under a variety of reactions conditions, and so on.Related Products of 172222-30-9

Blanco, Christian O.; Nascimento, Daniel L.; Fogg, Deryn E. published their research in Organometallics in 2021. The article was titled 《Routes to High-Performing Ruthenium-Iodide Catalysts for Olefin Metathesis: Ligand Lability Is Key to Efficient Halide Exchange》.Related Products of 172222-30-9 The article contains the following contents:

Clean, high-yielding routes are described to Ru-diiodide catalysts that were recently shown to enable high productivity in olefin metathesis. For the 2nd-generation Grubbs and Hoveyda catalysts (GII: RuCl2(H2IMes)(PCy3)(:CHPh); HII: RuCl2(H2IMes)(:CHAr), Ar = C6H4-2-OiPr), slow salt metathesis is shown to arise from the low lability of the ancillary PCy3 or ether ligands, which retards access to the four-coordinate intermediate required for efficient halide exchange. To exploit the lability of the 1st-generation catalysts, the diiodide complex RuI2(PCy3)(:CHAr) HI-I2 was prepared by treating Grubbs I (RuCl2(PCy3)2(:CHPh), GI) with NaI, H2C:CHAr (1a), and a phosphine-scavenging Merrifield iodide (MF-I) resin. Subsequent installation of H2IMes or cyclic (alkyl)(amino)carbene (CAAC) ligands afforded the 2nd-generation iodide catalysts in good to excellent yields. Given the incompatibility of the nitro group with a free carbene, the iodo-Grela catalyst RuI2(H2IMes)(:CHAr’) (nG-I2: Ar’ = C6H3-2-OiPr-4-NO2) was instead accessed by sequential salt metathesis of GI with NaI, installation of H2IMes, and finally cross-metathesis with the nitrostyrenyl ether H2C:CHAr’ (1b), with MF-I as the phosphine scavenger. The bulky iodide ligands improve the selectivity for macrocyclization in ring-closing metathesis. In the experiment, the researchers used Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Related Products of 172222-30-9)

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is a ruthenium-based olefin metathesis catalyst. It is useful for olefin cross metathesis (CM) and ring closing metathesis (RCM) of terminal olefins under a variety of reactions conditions, and so on.Related Products of 172222-30-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics