《Ru-Catalyzed cascade reaction of α,ω-alkynoic acids and arylethylamines towards the synthesis of aryl-fused heterocycles》 was published in Organic Chemistry Frontiers in 2020. These research results belong to Zheng, Yinying; Liu, Jiami; Lei, Xinsheng. COA of Formula: C43H72Cl2P2Ru The article mentions the following:
A simple, efficient and mild method for the preparation of aryl-fused heterocycles was developed using α,ω-alkynoic acids and arylethylamines. One of Grubbs’ ruthenium carbenes was able to catalyze the formation of exocyclic enol lactones from α,ω-alkynoic acids, which subsequently underwent aminolysis and N-acyl iminium ion formation/cyclization with arylethylamines in the presence of TFA, affording one kind of “”drug-privileged”” scaffold. Demonstrated with high functional group tolerance, this new cascade reaction endowed the Grubbs’ ruthenium carbene with a new synthetic utility beyond routine olefin metathesis. The experimental process involved the reaction of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9COA of Formula: C43H72Cl2P2Ru)
Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is a ruthenium-based olefin metathesis catalyst. It is useful for olefin cross metathesis (CM) and ring closing metathesis (RCM) of terminal olefins under a variety of reactions conditions, and so on.COA of Formula: C43H72Cl2P2Ru
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics