In 2019,Synthetic Communications included an article by Mallikarjun Reddy, Sura; Reddy, Bijivemula N.; Motakatla, Venkata Krishna Reddy; Gokanapalli, Anusha; Pathak, Madhvesh; Reddy, Peddiahgari Vasu Govardhana. Reference of (3-Fluorophenyl)boronic acid. The article was titled 《Pd-NHC catalyzed Suzuki-Miyaura couplings on 3-bromo-9H-pyrido[2,3-b]indole-6-sulfonamide》. The information in the text is summarized as follows:
A series of novel α-carboline derivatives such as 3-aryl-9H-pyrido[2,3-b]indole-6-sulfonamides were synthesized from the readily available low-cost raw material, benzotriazole which was subjected to nucleophilic aromatic substitution with 5-bromo-2-chloropyridine followed by sequential steps of cyclization, sulfonation, amidation and finally Suzuki-Miyaura coupling reactions. The C-C bond formation between 3-bromo-9H-pyrido[2.3-b]indole-6-sulfonamide and various boronic acids was achieved with more accessible palladium pre-catalyst, Pd-PEPPSI-IPr via Suzuki coupling under microwave condition in a short reaction time with excellent yields. After reading the article, we found that the author used (3-Fluorophenyl)boronic acid(cas: 768-35-4Reference of (3-Fluorophenyl)boronic acid)
(3-Fluorophenyl)boronic acid(cas: 768-35-4) can be used to make novel liquid crystalline fluorobiphenylcyclohexenes and difluoroterphenyls by palladium-catalyzed cross-couplings also used in the synthesis of o-phenylphenols as potent leukotriene B4 receptor agonists.Reference of (3-Fluorophenyl)boronic acid
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics