Application of 98-60-2In 2019 ,《TBAI-catalyzed selective synthesis of sulfonamides and β-aryl sulfonyl enamines: coupling of arenesulfonyl chlorides and sodium sulfinates with tert-amines》 was published in Organic & Biomolecular Chemistry. The article was written by Jiang, Hongmei; Tang, Xiaoyue; Xu, Zhihui; Wang, Huixian; Han, Kang; Yang, Xiaolan; Zhou, Yuanyuan; Feng, Yong-Lai; Yu, Xian-Yong; Gui, Qingwen. The article contains the following contents:
A simple, practical and metal-free method has been developed for the synthesis of sulfonamides RS(O)2N(R1)R2 (R = Ph, pyridin-3-yl, naphthalen-1-yl, 4-methoxyphenyl, etc.; R1 = Et, n-Pr, Me, benzyl; R2 = Et, Ph, benzyl, n-Pr; R1R2 = -(CH2)4-, -(CH2)5-, -(CH2)2O(CH2)2-) and β-arylsulfonyl enamines (E)-ArS(O)2CH=CHN(R3)R4 [Ar = Ph, thiophen-2-yl, naphthalen-2-yl, etc.; R3 = Et, Ph, i-Pr; R4 = Et, i-Pr] via the selective cleavage of C-N and C-H bonds through the iodine-catalyzed oxidation of arenesulfonyl chlorides RS(O)2Cl and sodium sulfinates ArS(O)2Na with tert-amines N(R1)(R2)R3 (R3 = H, Et, Me, Bn). The method uses com. available inexpensive catalysts and oxidants, and has a wide substrate scope and operational simplicity.4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Application of 98-60-2) was used in this study.
4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. Application of 98-60-2 The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics