COA of Formula: C9H7ClN2OOn May 31, 2010, Mohajeri, Afshan; Shahamirian, Mozhgan published an article in Journal of Physical Organic Chemistry. The article was 《Substituent effect on local aromaticity in mono and di-substituted heterocyclic analogs of naphthalene》. The article mentions the following:
A quant. study on local aromaticity has been performed on a series of mono- and di-substituted biheterocycles (quinoline, isoquinoline, quinoxaline, quinazoline). Three electronically based indexes (PDI, ATI, and FLU) have been employed to investigate the substituent effect on the π-electron delocalization in both heterocycle and benzenoid rings. Three typical substituents (Cl, OCH3, and CN) with different inductive and resonance power have been selected. Generally, substituent causes a reduction in aromaticity irresp. of whether it is electron attracting or electron donating. It is shown that the maximum aromaticity exhibits a similar trend of Cl > CN > OCH3 for all the studied rings. Moreover, it is found that the substituent situation with respect to the heteroatom has a significant influence on the aromaticity. It results from our study that in di-substituted derivatives, irresp. of whether the two substituents form a meta or para isomer, they preferably choose the position which leads to the maximum aromaticity character. Copyright © 2009 John Wiley & Sons, Ltd. The experimental process involved the reaction of 2-Chloro-5-methoxyquinoxaline(cas: 76052-76-1COA of Formula: C9H7ClN2O)
2-Chloro-5-methoxyquinoxaline(cas: 76052-76-1) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. COA of Formula: C9H7ClN2O However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics