Name: Thiophene-2-sulfonyl chlorideIn 2021 ,《One-pot synthesis of sulfonylhydrazones from sulfonyl chloride, hydrazine hydrate and vinyl azide in water》 was published in Journal of the Iranian Chemical Society. The article was written by Luo, Mengqiang; Wang, Hai; Ren, Xiaorong; Lu, Ruijuan; Qi, Chenze; Zhang, Yaohong; Shen, Runpu. The article contains the following contents:
A facile and eco-friendly protocol for the synthesis of sulfonylhydrazones I [R = Ph, 4-MeC6H4, 4-FC6H4, 4-ClC6H4, 4-BrC6H4; R1 = Me, Ph, 4-MeOC6H4, etc.] from sulfonyl chlorides, hydrazine hydrate and vinyl azides was developed. The unique advantage of this approach was that desired products could be obtained efficiently in water, which meets the requirements of green chem. and provided good perspectives for the sustainable production of new drug candidate. Also, this reaction proceeded in moderate to good yields with a wide tolerance of functional groups. In the part of experimental materials, we found many familiar compounds, such as Thiophene-2-sulfonyl chloride(cas: 16629-19-9Name: Thiophene-2-sulfonyl chloride)
Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Name: Thiophene-2-sulfonyl chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics