Synthetic Route of C6H11ClO3On March 31, 2009, Dolakova, Petra; Dracinsky, Martin; Fanfrlik, Jindrich; Holy, Antonin published an article in European Journal of Organic Chemistry. The article was 《Synthesis of analogues of acyclic nucleoside diphosphates containing a (phosphonomethyl)phosphanyl moiety and studies of their phosphorylation》. The article mentions the following:
Acyclic nucleoside diphosphonate derivatives of purines and pyrimidines were prepared by Mitsunobu reaction of suitably protected heterocyclic bases with alcs. containing the (phosphonomethyl)phosphanyl moiety. Also, nonhydrolyzable acyclic analogs of dUDP were prepared as potential inhibitors of dUTPase. Their phosphorylation to analogs of dUTP, however, gave mixtures of linear and branched phosphates. The courses of the phosphorylation reactions were followed by 31P NMR spectroscopy, and both phosphonate and phosphinate moieties react with 1,1′-carbonyldiimidazole and tri-n-butylammonium phosphate. The pKa values of the (phosphonomethyl)phosphanyl system were also determined by 31P NMR spectroscopy. In the experimental materials used by the author, we found 2-(2-Chloroethoxy)ethyl acetate(cas: 14258-40-3Synthetic Route of C6H11ClO3)
2-(2-Chloroethoxy)ethyl acetate(cas: 14258-40-3) belongs to aliphatic hydrocarbons. Aliphatic hydrocarbons belong to the most abundant fraction in crude oil. Aliphatics molecules are linear or branched open-chain structures such as n-alkanes, isoalkanes, cycloalkanes (naphthenes), terpenes and steranes.Synthetic Route of C6H11ClO3
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics