Nasiri Oskooie, Maryam; Pooresmaeil, Malihe; Namazi, Hassan published the artcile< Design and synthesis of vinylic glycomonomers and glycopolymer based on α-D-glucofuranose moieties>, Electric Literature of 1592-20-7, the main research area is vinylic glycomonomer glycopolymer glucofuranose moiety synthesis.
Carbohydrates are valuable and safe sources for the synthesis of biopolymers. Today, synthetic polymers having saccharides as pedant groups are one of the great interests in biochem. and the medicinal field. In this work, with the aim of preparing the new glyco-copolymer, firstly isopropylidene derivative of α-D-glucofuranose was synthesized from the reaction of acetone with the glucose in the presence of sulfuric acid as catalyst. Then the obtained compound sep. reacted with acryloyl chloride and ρ-(chloromethyl)styrene monomers to produce related vinylic type glycomonomers. The synthesized glycomonomers were purified using column chromatog. Characterization of the synthesized vinylic glycomonomers was carried out using elemental anal., fourier transform IR, Carbon-13NMR and proton NMR spectroscopy. In the next step, the obtained glycomonomers were copolymerized in 1:1 ratio via a fast and easy free radical polymerization technique. The obtained copolymer showed good solubility in various solvents such as THF, chloroform, Et acetate, and some of the other organic solvents. Finally, water-soluble glyco-copolymer was obtained via partial hydrolysis. The structure of the isolated copolymers determined using the 1H NMR, gel permeation chromatog., and FT-IR spectroscopy.
Journal of Polymer Research published new progress about Biocompatible materials. 1592-20-7 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H9Cl, Electric Literature of 1592-20-7.
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Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics