Gutorov, L. A.; Golovchinskaya, E. S. published the artcile< Syntheses in the purine series. XXXIV. Transformations of N,N'-dimethylxanthines in the reaction with phosphoryl chloride in the presence of tert-amines>, Electric Literature of 2382-10-7, the main research area is xanthine reaction phosphorus oxychloride; purine chloro methyl.
Purine derivative (I; X = OPOCl2) (II) was obtained in ∼18% yield by boiling theobromine with POCl3 in Me2NH for 8 hr. Hydrolysis of II with aqueous NaOH gave purine (I; X = Cl). Boiling the latter with PhCl afforded purine (III; R = p-Me2N- C6H4). III (R = Cl) was obtained in ∼90% yield by boiling theobromine with POCl3 containing Et3N·HCl.
Khimiko-Farmatsevticheskii Zhurnal published new progress about 2382-10-7. 2382-10-7 belongs to class chlorides-buliding-blocks, and the molecular formula is C6H4Cl2N4, Electric Literature of 2382-10-7.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics