Fonte, Melanie; Fagundes, Natalia; Gomes, Ana; Ferraz, Ricardo; Prudencio, Cristina; Araujo, Maria Joao; Gomes, Paula; Teixeira, Catia published the artcile< Development of a synthetic route towards N4,N9-disubstituted 4,9-diaminoacridines: On the way to multi-stage antimalarials>, Application of C8H7ClO3, the main research area is diaminoacridine preparation antimalarial drug.
This is the first multi-step synthetic route, which has been developed towards N4,N9-disubstituted 4,9-diaminoacridines I. The target structures I are likely to reveal interesting biol. activities in the near future, not only due to their mepacrine-like core, but also because they embed simultaneously the pharmacophores of chloroquine and primaquine, antimalarial drugs that act at different stages of malaria infection.
Tetrahedron Letters published new progress about Acridines Role: PAC (Pharmacological Activity), RCT (Reactant), SPN (Synthetic Preparation), THU (Therapeutic Use), BIOL (Biological Study), RACT (Reactant or Reagent), PREP (Preparation), USES (Uses). 22717-55-1 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H7ClO3, Application of C8H7ClO3.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics