Dubuffet, T.; Loutz, A.; Lavielle, G. published the artcile< An efficient large scale synthesis of coumarins by a dealkylative boron-mediated ring closure of 3-(ortho-methoxyaryl)propenoic esters>, HPLC of Formula: 53581-86-5, the main research area is coumarin synthesis; methoxyarylpropenoic ester preparation dealkylative boron mediated ring closure; methoxycinnamate ortho preparation dealkylative boron mediated ring closure.
Various substituted coumarins, e.g. I (R = H, 5-OH, 5-OMe, 6-OH, 8-OH, 6-Br, 7-Cl-6-Br, 6-Cl, 7-Cl, 8-Cl, 6-NO2, 7-F, 6-F), were prepared via a dealkylative boron-mediated ring closure of ortho-methoxycinnamates,e.g. II (R = H, 6-OMe, 5-OMe, 3-OMe, 5-Br, 5-Br-4-Cl, 5-Cl, 4-Cl, 3-Cl, 5-NO2, R1 = Me; R = 4-F, 5-F, R1 = Et).
Synthetic Communications published new progress about Cyclization (dealkylative). 53581-86-5 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H7ClO2, HPLC of Formula: 53581-86-5.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics