Chen, Honghao; Ouyang, Lufeng; Liu, Jidan; Shi, Wen-Jing; Chen, Guoshu; Zheng, Liyao published the artcile< Synthesis of Multisubstituted 1-Naphthoic Acids via Ru-Catalyzed C-H Activation and Double-Alkyne Annulation under Air>, Recommanded Product: 5-Chloroisobenzofuran-1,3-dione, the main research area is phthalic acid alkyne annulation ruthenium; naphthoic acid preparation; ruthenium annulation catalyst.
An efficient [2 + 2 + 2] benzannulation of phthalic acids/anhydrides with two alkynes was developed for synthesis of multisubstituted 1-naphthoic acids via Ru-catalyzed C-H activation. The reaction preceded well using atm. oxygen as the sole oxidant with high atom/step economies. Facilitated by the free carboxyl group, the products can be easily converted to diverse polycyclic mols.
Journal of Organic Chemistry published new progress about Air. 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, Recommanded Product: 5-Chloroisobenzofuran-1,3-dione.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics