In 2004,Bulletin of the Faculty of Pharmacy (Cairo University) included an article by El-Shemy, Khaled; El-Badry, Ossama; Roshdy, Sameha; El-Enany, Mervat. Product Details of 66662-48-4. The article was titled 《Synthesis of certain novel pyridothiopyranoindazoles as potential DNA intercalators in cancer chemotherapy》. The information in the text is summarized as follows:
A series of 5-chloro-8,10-dimethyl-2-(aminoethyl)pyrido[3′,2′:5,6]thiopyrano[4,3,2-cd]indazole, e.g., I, was obtained by reacting 5-chloro-8,10-dimethyl-2-(2-chloroethyl)pyrido[3′,2′:5,6]thiopyrano[4,3,2-cd]indazole with certain primary or secondary amines. The in vitro cytotoxic effect of selected samples of the synthesized compounds were also achieved. The two synthesized series have structural relationship to certain anthrapyrazoles and benzothiopyranoindazoles which have been reported as potent antitumor agents. The experimental process involved the reaction of 2-Chloro-4,6-dimethylnicotinic acid(cas: 66662-48-4Product Details of 66662-48-4)
2-Chloro-4,6-dimethylnicotinic acid(cas: 66662-48-4) belongs to pyridine. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year.Product Details of 66662-48-4
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics