The author of 《Synthesis and biological activity of certain pyridobenzodiazepine derivatives》 were Botros, Samir; El-Gendy, Adel A.; Said, Mohamed M.; Oma, Adel H.. And the article was published in Bulletin of the Faculty of Pharmacy (Cairo University) in 2001. Recommanded Product: 66662-48-4 The author mentioned the following in the article:
The present work comprises the synthesis of 6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepine-5-one derivatives by condensation of 2-chloro-4,6-dimethylnicotinic acid with 1,2-phenylenediamines using 1-butoxyethanol as solvent. Monoalkylation of the products using one equivalent of the appropriate alkyl halide and 30% NaOH in DMSO gave the 6-alkyl derivatives. Some of the prepared compounds were screened for CNS depressant and anticonvulsant activities. After reading the article, we found that the author used 2-Chloro-4,6-dimethylnicotinic acid(cas: 66662-48-4Recommanded Product: 66662-48-4)
2-Chloro-4,6-dimethylnicotinic acid(cas: 66662-48-4) belongs to pyridine. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year.Recommanded Product: 66662-48-4
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics