Bera, Shyamal Kanti; Mal, Prasenjit published the artcile< Mechanochemical-Cascaded C-N Cross-Coupling and Halogenation Using N-Bromo- and N-Chlorosuccinimide as Bifunctional Reagents>, Category: chlorides-buliding-blocks, the main research area is phenanthridinone derivative preparation crystal structure mol; biphenyl carboxamide halosuccinimide cascade cross coupling halogenation.
Direct synthesis of halo-substituted phenanthridinone derivatives I [R = Cl, Br, I; R1 = H, 3-Me, 3-F, etc.; R2 = H, 8-Me; R3 = OMe, Ph] was achieved via cascade C-N bond formation and subsequent halogenation reactions of N-halosuccinimides with N-methoxy-[1,1′-biphenyl]-2-carboxamides. During the reactions, NBS/NCS first assisted the oxidative C-N coupling reaction and subsequently promoted a halogenation reaction. Thus, the role of NBS/NCS was established to be bifunctional. This protocol offered a mild, solvent-free, convenient, one-pot synthesis of compounds I.
Journal of Organic Chemistry published new progress about Aromatic amides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 128-09-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C4H4ClNO2, Category: chlorides-buliding-blocks.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics