Zweig, Arnold; Epstein, Martin published the artcile< 3-Chlorophthalic anhydride through chlorination of phthalic anhydride>, Recommanded Product: 5-Chloroisobenzofuran-1,3-dione, the main research area is chlorophthalic anhydride; phthalic anhydride chlorination.
Monochlorination of molten phthalic anhydride in the presence of FeCl3 proceeds with only a small preference (55:45) for 4-chlorophthalic anhydride over 3-chlorophthalic anhydride. Under the same conditions both monochlorophthalic anhydrides are chlorinated at rates comparable to that of phthalic anhydride itself. When 1 mol of Cl is taken up by 1 mol of phthalic anhydride, a mixture of starting material and mono- and dichlorophthalic anhydrides is obtained together with traces of the more highly chlorinated phthalic anhydrides. Distillative separation of 3-chlorophthalic anhydride from the lower boiling 4-chlorophthalic anhydride can be readily achieved on a moderately efficient column. Convenient preparation of pure 3-chlorophthalic anhydride through distillation of chlorinated phthalic anhydride mixtures is impeded by the nearly identical b.ps. of 3-chlorophthalic anhydride and 4,5-dichlorophthalic anhydride. The latter is formed to the extent of 1/6 of the dichlorophthalic anhydride fraction of the chlorinated mixtures
Journal of Organic Chemistry published new progress about Chlorination. 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, Recommanded Product: 5-Chloroisobenzofuran-1,3-dione.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics