Zhou, Yu; Yang, Cheng-Li; Ye, Lei; Dong, Zhi-Bing published the artcile< Copper-Catalyzed C-S Formation for the Synthesis of Benzyl Phenyl Sulfides from Dithiocarbamates>, Recommanded Product: 1-Chloro-2-(chloromethyl)benzene, the main research area is benzyl phenyl sulfide green preparation; phenyl dithiocarbamate benzyl halide coupling copper catalyst.
An odorless and efficient protocol for the synthesis of benzyl Ph sulfides RSCH2R1 [R = Ph, 2-MeC6H4, 4-ClC6H4, etc.; R1 = Ph, 4-MeOC6H4, 2-BrC6H4, etc.] was reported. Starting from environmentally friendly Ph dithiocarbamates and com. available benzyl halides as starting materials, the target compounds (benzyl Ph sulfides) could be obtained smoothly and easily by using copper salt as catalyst and Cs2CO3as base. This method featured ligand/additive-free, the use of readily available starting materials, inexpensive catalysts, and good substrate suitability, illustrating its potentially synthetic value for the convenient preparation of some biol. active mols.
Synthesis published new progress about Benzyl halides Role: RCT (Reactant), RACT (Reactant or Reagent). 611-19-8 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H6Cl2, Recommanded Product: 1-Chloro-2-(chloromethyl)benzene.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics