Warner, Andrew J.; Lawson, James R.; Fasano, Valerio; Ingleson, Michael J. published the artcile< Formation of C(sp2)-boronate esters by borylative cyclization of alkynes using BCl3>, Quality Control of 16799-05-6, the main research area is cyclization borylative alkyne aryl boron trichloride preparation cyclic alkenylboronate; fluorenyl azafluorenyl boronate preparation dipropargyl compound cyclization boron trichloride; intramol borylation arylalkyne arene boron trichloride preparation diaryl vinylboronate; alkynes; boron; cyclizations; heterocycles; synthetic methods.
Arylpropargyl compounds R1C6H4YCH2CCR2 undergo cyclization in a reaction with BCl3 and pinacol, yielding cyclic alkenylboronates I (2, R1 = H, Me, MeO, Cl; Y = CH2, NTs, O; R2 = Ph, ClC6H4, C6F5, 3-CF3C6H4, 4-NCC6H4, MeC6H4, Br, Me, 1-naphthyl, PhCH:CH, 4-NO2C6H4, 4-EtO2CC6H4). Diynes R3CCCH2YCH2CCR3 gave boronates II (R3 = Ph, 10a,b; Y = CH2, NTs) or III (11, R3 = H, Y = CH2). BCl3 is an inexpensive electrophile which induces the borylative cyclization of a wide range of substituted alkynes to regioselectively form polycycles containing synthetically versatile C(sp2)-boronate esters. It proceeds rapidly, with good yields and is compatible with a range of functional groups and substitution patterns. Intermol. 1,2-carboboration of alkynes Ar1CCMe is also achieved using BCl3 and arene Ar2H to generate trisubstituted vinyl boronate esters Ar1Ar2C:CMe(Bpin) (12, Ar1 = Ph, Ar2 = 5-methyl-2-thienyl).
Angewandte Chemie, International Edition published new progress about Alkynes, aryl Role: RCT (Reactant), RACT (Reactant or Reagent). 16799-05-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H8BrCl, Quality Control of 16799-05-6.
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Chloride – Wikipedia,
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