Gonzalez-Marino, Iria; Quintana, Jose Benito; Rodriguez, Isaac; Cela, Rafael published the artcile< Evaluation of the occurrence and biodegradation of parabens and halogenated by-products in wastewater by accurate-mass liquid chromatography-quadrupole-time-of-flight-mass spectrometry (LC-QTOF-MS)>, Application In Synthesis of 3964-57-6, the main research area is LCMS evaluation paraben wastewater halogenated compound biodegradation.
An assessment of the sewage occurrence and biodegradability of 7 parabens and 3 halogenated derivatives of Me paraben (MeP) is presented. Several wastewater samples were collected at 3 different wastewater treatment plants (WWTPs) during Apr. and May 2010, concentrated by solid-phase extraction (SPE) and analyzed by liquid chromatog.-electrospray-quadrupole-time-of-flight mass spectrometry (LC-QTOF-MS). The performance of the QTOF system proved to be comparable to triple-quadrupole instruments in terms of quant. capabilities, with good linearity (R2 > 0.99 in the 5-500 ng mL-1 range), repeatability (relative standard deviation < 5.6%) and LODs (0.3-4.0 ng L-1 after SPE). MeP and Pr paraben (PrP) were the most frequently detected and the most abundant analytes in raw wastewater (0.3-10 μg L-1), in accordance with the data displayed in the bibliog. and reflecting their wider use in cosmetic formulations. Samples were also evaluated in search for potential halogenated byproducts of parabens, formed as a result of their reaction with residual Cl contained in tap H2O. Monochloro- and dichloro-Me paraben (ClMeP and Cl2MeP) were found and quantified in raw wastewater at levels between 0.01 and 0.1 μg L-1. Halogenated derivatives of PrP could not be quantified due to the lack of standards; nevertheless, the monochlorinated species (ClPrP) was identified in several samples from its accurate precursor and product ions mass/charge ratios (m/z). Removal efficiencies of parabens and MeP chlorinated byproducts in WWTPs exceeded 90%, with the lowest percentages corresponding to the latter species. This trend was confirmed by an activated sludge biodegradation batch test, where nonhalogenated parabens had half-lives < 4 days, whereas halogenated derivatives of MeP turned out to be more persistent, with up to 10 days of half-life in the case of dihalogenated derivatives A further stability test performed with raw wastewater also showed that parabens degrade rapidly in real sewage, with half-lives < 10 h for n-butyl-paraben, while dihalogenated species again turned out to be more stable, with half-lives longer than a week. Water Research published new progress about Biodegradation kinetics. 3964-57-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H7ClO3, Application In Synthesis of 3964-57-6.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics