Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 3900-89-8, formula is C6H6BClO2, Name is (2-Chlorophenyl)boronic acid. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Quality Control of 3900-89-8.
Guo, Yuying;Chen, Jiabao;Ren, Dan;Du, Bo;Wu, Lei;Zhang, Yuanyuan;Wang, Zhouyu;Qian, Shan research published 《 Synthesis of osthol-based botanical fungicides and their antifungal application in crop protection》, the research content is summarized as follows. Plant pathogenic fungi decrease the quality and productivity of plant production The botanical fungicides have better biocompatibility and rapid biodegradation, little or no cross resistance, and the structural diversity, and thus are beneficial to deal with plant fungal diseases. Osthole has been widely used as the com. botanical fungicide against powdery mildew in China. In this article, a series of osthole derivatives were synthesized, which resp. contain different substituents on the benzene ring, at the C8-position and pyrone ring. All the target compounds were evaluated in vitro for their antifungal activity against resistant phytopathogenic fungi. Colletotrichum fragariae, Strawberry Botrytis cinerea, Kiwifruit Botrytis cinerea, Kiwifruit brown Rots, which are common in fruit fungal diseases. The compound 7-hydroxy-8-methyl-4-(trifuoromethyl)-2H-chromen-2-one (I) was identified as the most promising candidate with the EC50 values at 38.7μg/mL against Colletotrichum Fragariae, 14.5μg/mL against Strawberry Botrytis Cinerea and 24.3μg/mL against Kiwifruit Botrytis Cinerea, resp., whereas the antifungal activity against resistant phytopathogenic fungi. of osthole is too low to be used (EC50 > 400 ppm). The results of mycelial relative conductivity determination, PI uptake and fluorescence spectroscopy indicated that the cell membrane of fungi is the key action site of I. Besides, I has the potent inhibitory activity against both of plant and human pathogenic bacteria. Our studies showed that C4 was worthy for further attention as a promising botanical fungicide candidate in crop protection.
3900-89-8, 2-Chlorophenylboronic acid is a useful research compound. Its molecular formula is C6H6BClO2 and its molecular weight is 156.38 g/mol. The purity is usually 95%.
2-Chlorophenylboronic acid used in the preparation of imidazo[1,2-a]pyridine amides which has tuberculostatic activity.
2-Chlorophenylboronic acid is a diphenyl ether that can be used as a building block for the synthesis of benzodiazepine receptor ligands. It has been shown to be an efficient nucleophile, leading to the formation of carbonyl groups in the presence of halides. 2-Chlorophenylboronic acid has also been shown to inhibit p38 kinase activity and may be useful for anticancer therapy., Quality Control of 3900-89-8
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics