The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 6334-18-5, formula is C7H4Cl2O, Name is 2,3-Dichlorobenzaldehyde. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Related Products of 6334-18-5.
Govindaraju, Santhosh;Tabassum, Sumaiya research published 《 Sulphuric acid supported silica gel (H2SO4-SiO2) as an efficient catalyst for one-pot multicomponent synthesis of pyrano[2,3-c]pyrazol-amines under ultrasonication》, the research content is summarized as follows. In this study, the catalytic potential of a novel heterogeneous catalyst-sulfuric acid supported on silica gel (H2SO4-SiO2) has been assessed for the one-pot cyclo condensation reaction of aromatic aldehydes RCHO (R = 2-chlorophenyl, 2,4-dichlorophenyl, 2-hydroxy 5-bromophenyl, etc.), phenylacetonitriles 4-R1-C6H4CH2CN (R1 = F, NO2), Et acetoacetate and hydrazine to furnish poly functionalized pyrano[2,3-c]pyrazol-amine scaffolds I under ultrasonication. Notably, within the framework of green chem., this divergent and step-economic approach has many benefits such as (i) use of water as solvent in the reaction, (ii) creation of up to five bonds in one sequence, (iii) avail of US irradiation as an efficient source of energy, (iv) application of nontoxic and reusable catalyst. Besides these, simple workup procedure, low catalyst loadings, shorter reaction time, high functional group compatibility, readily accessible starting materials and excellent yields without column chromatog. render this protocol novel and greener towards the synthesis of poly functionalized pyrano[2,3-c]pyrazol-amines I.
Related Products of 6334-18-5, 2,3-Dichlorobenzaldehyde(2,3-DBA)is a useful research compound. Its molecular formula is C7H4Cl2O and its molecular weight is 175.01 g/mol. The purity is usually 95%.
2,3-DBA is an organic compound that is used as a synthetic intermediate in the preparation of other chemicals. It is prepared by reacting 2-chloroacetophenone with hydrochloric acid and sodium carbonate in a reaction vessel. The product can be purified through fractional distillation or crystallization. The optical properties of 2,3-DBA are determined by its dipole moment and the substituents attached to the methylene group. Molecular modeling studies have shown that felodipine can bind to 2,3-DBA through its active methylene group. The reaction products between sulfadiazine and 2,3-DBA are pyridinedicarboxylic acid and 3-chlorobenzaldehyde.
2,3-DBA is part of a group of Benzaldehyde (B119740) derivatives that exhibit activity against Mycobacterium tuberculosis, the bacteria responsible for causing tuberculosis in humans. 2,3-DBA is also used as a reagent to synthesize (E)-2-(2-arylhydrazinyl)quinoxalines, compounds that have potent anticancer activity., 6334-18-5.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics