Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 12112-67-3, formula is C16H24Cl2Ir2, Name is Chloro(1,5-cyclooctadiene)iridium(I) dimer. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Safety of Chloro(1,5-cyclooctadiene)iridium(I) dimer.
Gao, Zhaofeng;Liu, Jingwen;Huang, Haizhou;Geng, Huiling;Chang, Mingxin research published 《 An Iridium Catalytic System Compatible with Inorganic and Organic Nitrogen Sources for Dual Asymmetric Reductive Amination Reactions》, the research content is summarized as follows. Herein efforts on merging two asym. reductive amination (ARA) reactions into a single-step transformation was reported. Catalyzed by a complex formed from iridium and a steric hindered phosphoramidite, readily available and inexpensive aromatic ketones initially underwent the first ARA with ammonium acetate to afford primary amines, which served as the amine sources for the second ARA, and finally provided the enantiopure C2-sym. secondary amine products. The developed process competently enabled the successive coupling of inorganic and organic nitrogen sources with ketones in the same reaction system. The Bronsted acid additive played multiple roles in this procedure: it accelerated the formation of imine intermediates, minimized the inhibitory effect of N-containing species on the iridium catalyst, and reduced the primary amine side products.
Safety of Chloro(1,5-cyclooctadiene)iridium(I) dimer, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
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Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics