Chlorinated organic compounds are found in nearly every class of biomolecules. 1878-65-5, formula is C8H7ClO2, Name is 3-Chlorophenylacetic acid. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. Recommanded Product: 3-Chlorophenylacetic acid.
Cheng, Aolin;Zhang, Liangliang;Zhou, Qinghai;Liu, Tao;Cao, Jing;Zhao, Guoqing;Zhang, Kun;Song, Guanshui;Zhao, Baoguo research published 《 Efficient asymmetric biomimetic aldol reaction of glycinates and trifluoromethyl ketones by carbonyl catalysis》, the research content is summarized as follows. The direct asym. aldol reaction of glycinates represents an intriguing and straightforward strategy to make biol. significant chiral β-hydroxy-α-amino-acid derivatives But it is not easy to realize the transformation due to the disruption of the reactive NH2 group of glycinates. Inspired by the enzymic aldol reaction of glycine, we successfully developed an asym. aldol reaction of glycinate, NH2-CH2 CO-O-tert-Bu, and trifluoromethyl ketones with 0.1-0.0033 mol % of chiral N-Me pyridoxal (I) as the catalyst, producing chiral β-trifluoromethyl-β-hydroxy-α-amino-acid esters 6 in 55-82% yields (for the syn-diastereomers) with up to >20:1 dr and 99% ee under very mild conditions. The reaction proceeds via a catalytic cycle similar to the enzymic aldol reaction of glycine. Pyridoxal catalyst I activates both reactants at the same time and brings them together in a specific spatial orientation, accounting for the high efficiency as well as excellent diastereo- and enantioselectivities.
1878-65-5, 3-Chlorophenylacetic acid is a useful research compound. Its molecular formula is C8H7ClO2 and its molecular weight is 170.59 g/mol. The purity is usually 95%.
3-Chlorophenyl acetic acid is a compound that has resonance mass of 269. The compound reacts with HBr and water to produce 3-chlorobenzene, carbon dioxide and hydrogen chloride. A reaction product of this chemical is covid-19 pandemic (a type of drug)., Recommanded Product: 3-Chlorophenylacetic acid
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics