Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Electric Literature of 2905-24-0.
Bourbon, Paul;Appert, Emeline;Martin-Mingot, Agnes;Michelet, Bastien;Thibaudeau, Sebastien research published 《 Complementary Site-Selective Sulfonylation of Aromatic Amines by Superacid Activation》, the research content is summarized as follows. Under superacidic conditions, aniline and indole derivatives such as p-methylacetanilide, 2-chloroacetanilide, oxindole, 2-methylindole, etc. are sulfonylated at low temperature with easy-to-access arenesulfonic acids or arenesulfonyl hydrazides ArS(O)2Y (Ar = Ph, 4-fluorophenyl, naphthalen-2-yl, etc.; Y = OH, NHNH2). By modification of the functional-group directing effect through protonation, this method allows nonclassical site functionalization by overcoming the innate regioselectivity of electrophilic aromatic substitution. This superacid-mediated sulfonylation of arenes RS(O)2Ar [R = 5-acetamido-2-methylbenzen-1-yl, 2,3,4,9-tetrahydro-1H-carbazol-7-yl, 4-[(2S)-2-acetamido-3-methoxy-3-oxopropyl]benzen-1-yl, etc.] is complementary to existing methods and can be applied, through protection by protonation, to the late-stage site-selective functionalization of natural alkaloids I and active pharmaceutical ingredients.
Electric Literature of 2905-24-0, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., 2905-24-0.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics