In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Direct Construction of Diverse Polyheterocycles Bearing Pyrrolidinediones via Rh(III)-Catalyzed Cascade C-H Activation/Spirocyclization, published in 2019, which mentions a compound: 4144-22-3, mainly applied to quinazolinone maleimide rhodium catalyst tandem Michael reaction spirocyclization; spiroisoindoloquinazolinepyrrolidine trione preparation; spiropolyheterocycle preparation, COA of Formula: C8H11NO2.
Rh(III)-catalyzed cascade oxidative annulation of 2-arylquinazolinones with various maleimides to afford spiroisoindoloquinazolinones bearing pyrrolidinediones was described. Sequential ortho C-H functionalization and spirocyclization via aza-Michael addition result in the formation of both C-C and C-N bonds in a single operation. This atom- and step-economic strategy provides an efficient and novel approach for the syntheses of diverse polyheterocycles bearing pyrrolidinediones, starting from 2-heteroarylquinazolinones and 5-arylpyrazolopyrimidinones, in good to excellent yields.
Compound(4144-22-3)COA of Formula: C8H11NO2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(1-(tert-Butyl)-1H-pyrrole-2,5-dione), if you are interested, you can check out my other related articles.
Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics