COA of Formula: C7H4Cl2O2. In 2020.0 ADV SYNTH CATAL published article about HIGHLY EFFICIENT SYNTHESIS; CROSS-COUPLING REACTIONS; CARBOXYLIC-ACIDS; DECARBONYLATIVE BORYLATION; AMIDES; REDUCTION; ESTERS; CHLORIDES; TRANSAMIDATION; HYDROGENATION in [He, Zhanyu; Wang, Zijia; Ru, Junxiang; Wang, Yulin; Liu, Tingting; Zeng, Zhuo] South China Normal Univ, Sch Chem, Guangzhou 510006, Peoples R China; [Zeng, Zhuo] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China in 2020.0, Cited 80.0. The Name is 2,6-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-30-6.
We report the catalytic reduction of both active esters and amides by selective C(acyl)-X (X=O, N) cleavage to access aldehyde functionality via a palladium-catalyzed strategy. Reactions are promoted by hydrosilanes as reducing reagents with good to excellent yields and with excellent chemoselectivity for C(acyl)-N and C(acyl)-O bond cleavage. Carboxylic acid C(acyl)-O bonds are activated by 2-chloro-4,6-dimethoxy-1,3,5-triazine (CDMT) to form triazine ester intermediates, which further react with hydrosilanes to yield aldehydes in one-pot two-step procedures. We demonstrate that C(acyl)-O cleavage/formylation offers higher yields and broader substrate scopes compared with C(acyl)-N cleavage under the same reaction conditions.
Welcome to talk about 50-30-6, If you have any questions, you can contact He, ZY; Wang, ZJ; Ru, JX; Wang, YL; Liu, TT; Zeng, Z or send Email.. COA of Formula: C7H4Cl2O2
Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics