Category: chlorides-buliding-blocks. I found the field of Biochemistry & Molecular Biology; Chemistry; Pharmacology & Pharmacy very interesting. Saw the article Synthesis, characterization, antimicrobial, antioxidant and computational evaluation of N-acyl-morpholine-4-carbothioamides published in 2021, Reprint Addresses Aziz, H (corresponding author), Quaid I Azam Univ, Dept Chem, Islamabad 45320, Pakistan.. The CAS is 50-84-0. Through research, I have a further understanding and discovery of 2,4-Dichlorobenzoic acid.
The present research paper reports the convenient synthesis, successful characterization, in vitro antibacterial, antifungal, antioxidant potency and biocompatibility of N-acyl-morpholine-4-carbothioamides (5a-5j). The biocompatible derivatives were found to be highly active against the tested bacterial and fungal strains. Moreover, some of the screened N-acyl-morpholine-4-carbothioamides exhibited excellent antioxidant potential. Docking simulation provided additional information about possibilities of their inhibitory potential against RNA. It has been predicted by in silico investigation of the binding pattern that compounds 5a and 5j can serve as the potential surrogate for design of novel and potent antibacterial agents. The results for the in vitro bioassays were promising with the identification of compounds 5a and 5j as the lead and selective candidate for RNA inhibition. Results of the docking computations further ascertained the inhibitory potential of compound 5a. Based on the in silico studies, it can be suggested that compounds 5a and 5j can serve as a structural model for the design of antibacterial agents with better inhibitory potential. [GRAPHICS] .
Welcome to talk about 50-84-0, If you have any questions, you can contact Aziz, H; Saeed, A; Khan, MA; Afridi, S; Jabeen, F or send Email.. Category: chlorides-buliding-blocks
Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics