Month: November 2021

An article Risk assessment of volatile organic compounds (VOCs) detected in sanitary pads WOS:000477139900001 published article about EXPOSURE; DIOXINS; ABSORPTION; PRODUCTS; CHLORINE; SKIN in [Kim, Hyang Yeon; Kim, Ji-Young; Kim, Kyu-Bong] Dankook Univ, Coll Pharm, 119 Dandae Ro, Cheonan 31116, South Korea; [Lee, Jung Dae; Lee, Byung-Mu] Sungkyunkwan Univ, Coll Pharm, Div Toxicol, Suwon, South Korea; [Lee, Joo Young] Catholic Univ Korea, Coll Pharm, BK21plus Team, Bucheon, South Korea; [Bae, Ok-Nam] Hanyang Univ, Coll Pharm, Ansan, South Korea; [Choi, Yong-Kyu; Baek, Eunji; Kang, Sejin; Min, Chungsik; Seo, Kyungwon; Choi, Kihwan] Minist Food & Drug Safety, Pharmaceut & Med Devices Res Dept, Cosmet Res Team, Natl Inst Food & Drug Safety Evaluat, Osong, South Korea in 2019, Cited 112. Product Details of 95-49-8. The Name is 1-Chloro-2-methylbenzene. Through research, I have a further understanding and discovery of 95-49-8

Disposable sanitary pads are a necessity for women’s health, but safety concerns regarding the use of these products have created anxiety. The aim of this study was to conduct a risk assessment of 74 volatile organic compounds (VOCs), which were expected to be contained within sanitary pads. Of the 74 VOCs, 50 were found in sanitary pads retailed in Korea at concentrations ranging from 0.025 to 3548.09 mu g/pad. In order to undertake a risk assessment of the VOCs, the toxicological database of these compounds in the United States Environmental Protection Agency (USEPA), Agency for Toxic Substances and Disease Registry (ATSDR), National Toxicology Program (NTP) and World Health Organization (WHO) was searched. Ethanol was found to exhibit the highest reference dose (RfD) while 1,2-dibromo-3-chloro-propane displayed the lowest RfD. Consequently, a worst-case exposure scenario was applied in this study. It was assumed that there was the use of 7.5 sanitary napkins/day for 7 days/month. In the case of panty liners or overnight sanitary napkins, the utilization of 90 panty liners/month or 21 overnight sanitary napkins/month was assumed, respectively. In addition, 43 kg, the body weight of 12 to 13-year-old young women, and 100% VOCs skin absorption were employed for risk assessment. The systemic exposure dose (SED) values were calculated ranging from 1.74 (1,1,2-trichloroethane) ng/kg/day to 144.4 (ethanol, absolute) mu g/kg/day. Uncertainty factors (UFs) were applied ranging from 10 to 100,000 in accordance with the robustness of animal or human experiments. The margin of exposure (MOE) of 34 VOCs was more than 1 (acceptable MOE > 1). Applicable carcinogenic references reported that the cancer risk of five VOCs was below 10(-6). Based on our findings, evidence indicates that the non-cancer and cancer risks associated with VOCs detected in sanitary pads currently used in South Korea do not pose an adverse health risk in women.

Product Details of 95-49-8. Welcome to talk about 95-49-8, If you have any questions, you can contact Kim, HY; Lee, JD; Kim, JY; Lee, JY; Bae, ON; Choi, YK; Baek, E; Kang, S; Min, C; Seo, K; Choi, K; Lee, BM; Kim, KB or send Email.

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Authors Ray, R; Hartwig, JF in WILEY-V C H VERLAG GMBH published article about in [Ray, Ritwika; Hartwig, John F.] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA in 2021.0, Cited 67.0. Quality Control of 1-Chloro-2-methylbenzene. The Name is 1-Chloro-2-methylbenzene. Through research, I have a further understanding and discovery of 95-49-8

Here, we report a class of ligands based on oxalohydrazide cores and N-amino pyrrole and N-amino indole units that generates long-lived copper catalysts for couplings that form the C-O bonds in biaryl ethers. These Cu-catalyzed coupling of phenols with aryl bromides occurred with turnovers up to 8000, a value which is nearly two orders of magnitude higher than those of prior couplings to form biaryl ethers and nearly an order of magnitude higher than those of any prior copper-catalyzed coupling of aryl bromides and chlorides. This ligand also led to copper systems that catalyze the coupling of aryl chlorides with phenols and the coupling of aryl bromides and iodides with primary benzylic and aliphatic alcohols. A wide variety of functional groups including nitriles, halides, ethers, ketones, amines, esters, amides, vinylarenes, alcohols and boronic acid esters were tolerated, and reactions occurred with aryl bromides in pharmaceutically related structures.

Welcome to talk about 95-49-8, If you have any questions, you can contact Ray, R; Hartwig, JF or send Email.. Quality Control of 1-Chloro-2-methylbenzene

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Authors Wang, YW; Jiang, XM; Wang, BQ in ROYAL SOC CHEMISTRY published article about CONJUGATE ADDITION; CARBON-DIOXIDE; HALIDES; BROMIDES; PALLADIUM; SYSTEM in [Wang, Yanwei; Jiang, Xiaomei; Wang, Baiquan] Nankai Univ, Coll Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China; [Wang, Baiquan] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China in 2020, Cited 45. Recommanded Product: 95-49-8. The Name is 1-Chloro-2-methylbenzene. Through research, I have a further understanding and discovery of 95-49-8

The transition-metal-catalyzed carboxylation of aryl and vinyl chlorides with CO2 is rarely studied, and has been achieved only with a Ni catalyst or combination of palladium and photoredox. In this work, the cobalt-catalyzed carboxylation of aryl and vinyl chlorides and bromides with CO2 has been developed. These transformations proceed under mild conditions and exhibit a broad substrate scope, affording the corresponding carboxylic acids in good to high yields.

Recommanded Product: 95-49-8. Welcome to talk about 95-49-8, If you have any questions, you can contact Wang, YW; Jiang, XM; Wang, BQ or send Email.

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Category: chlorides-buliding-blocks. In 2020 CATAL LETT published article about METAL-ORGANIC FRAMEWORKS; AEROBIC OXIDATION; CYCLOHEXANE OXIDATION; GREEN CHEMISTRY; TOLUENE; EFFICIENT; PERFORMANCE; PORPHYRINS; MANGANESE; COMPLEX in [Shen, Hai-Min; Qi, Bei; Hu, Meng-Yun; Liu, Lei; Ye, Hong-Liang; She, Yuan-Bin] Zhejiang Univ Technol, Coll Chem Engn, State Key Lab Breeding Base Green Chem Synth Tech, Hangzhou 310014, Peoples R China in 2020, Cited 75. The Name is 2,4-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-84-0.

A protocol for solvent-free and additive-free oxidation of primary benzylic C-H bonds with O(2)was presented through adjusting the combination of metalloporphyrins and NHPI as binary catalysts to overcome the deficiencies encountered in current oxidation systems. The effects of reaction temperature, porphyrin structure, central metal, catalyst loading and O(2)pressure were investigated systematically. For the optimized combination of T(2-OCH3)PPCo and NHPI, all the primary benzylic C-H bonds could be functionalized efficiently and selectively at 120 degrees C and 1.0 MPa O(2)with aromatic acids as the primary products. The selectivity towards aromatic acids could reach up to 70-95% in the conversion of more than 30% for most of the substrates possessing primary benzylic C-H bonds in the metalloporphyrin loading of 0.012% (mol/mol). And the superior performance of T(2-OCH3)PPCo among the metalloporphyrins investigated was mainly attributed to its high efficiency in charge transfer and fewer positive charges around central metal Co (II) which favored the adduction of O-2 to cobalt (II) forming the high-valence metal-oxo complex followed by the production of phthalimide N-oxyl radical (PINO) and the initiation of the catalytic oxidation cycle. This work would provide not only an efficient protocol in utilization of hydrocarbons containing primary benzylic C-H bonds, but also a significant reference in the construction of more efficient C-H bonds oxidation systems Graphic Abstract The solvent-free and additive-free oxidation of primary benzylic C-H bonds with O(2)was presented through adjusting the combination of metalloporphyrins and NHPI as binary catalysts, and the highest selectivity towards aromatic acid reached up to 95.1% with the conversion of 88.5% in the optimized combination of T(2-OCH3)PPCo and NHPI. [GRAPHICS] .

Bye, fridends, I hope you can learn more about C7H4Cl2O2, If you have any questions, you can browse other blog as well. See you lster.. Category: chlorides-buliding-blocks

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Liu, Y; Zhang, S; Li, CY; Shi, XH; Zhao, SN; Sun, B; Zhu, YH in [Liu, Yu; Zhang, Sheng; Li, Changyou; Shi, Xiaohong; Zhao, Shengnan; Sun, Biao; Zhu, Yonghua] Inner Mongolia Agr Univ, Water Conservancy & Civil Engn Coll, Hohhot 010018, Peoples R China published A modified QWASI model for fate and transport modeling of Zn and Pb in a shallow lake during the ice-free period in 2019.0, Cited 35.0. Quality Control of 2,6-Dichlorobenzoic acid. The Name is 2,6-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-30-6.

Heavy metal pollution in lakes is becoming increasingly of interest to researchers. Because heavy metals have high mobility and do not degrade, they migrate easily between different environmental mediums through processes such as suspended solids deposition, sediment resuspension, and diffusion, among others. These processes are particularly pronounced in shallow lakes since the hydrodynamism is higher in bodies of water with minimal depth. Lake Ulansuhai a typical shallow lake in the Hetao irrigation district in Inner Mongolia-also experiences intense sandstorm activity, which compounds the suspended solids exchange intensity between water and sediment, strengthening the migration of heavy metals in the lake system. This study examines the fate and transport of two heavy metals-Zn and Pb-within this lake, using a field experiment to determine the flux of sediment re-suspension and deposition and a laboratory experiment to modify the QWASI model for shallow bodies of water. The aguivalence and mass balance approaches were used to develop this modified QWASI model. The margins of error between the modeled and the measured average concentrations of Zn and Pb in water were 5.0%-30.6% and 5.8%-29.5%, respectively, and in sediment were 0.3%-4.9% and 0.9-5.5%, respectively. These results suggest that the modified QWASI model developed here could indeed be used to more accurately represent the fate and transport of Zn and Pb during the icefree period of a shallow lake. (C) 2013 Elsevier B.V. All rights reserved.

Welcome to talk about 50-30-6, If you have any questions, you can contact Liu, Y; Zhang, S; Li, CY; Shi, XH; Zhao, SN; Sun, B; Zhu, YH or send Email.. Quality Control of 2,6-Dichlorobenzoic acid

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

An article Palladium-Catalyzed C-2 and C-3 Dual C-H Functionalization of Indoles: Synthesis of Fluorinated Isocryptolepine Analogues WOS:000538848600011 published article about ARYLATION; ALKYNES; INDOLOQUINOLINES; ACTIVATION; ACCESS; HYDROARYLATION; ANNULATION; ALKALOIDS in [Chen, Chen; Wang, Yuebo; Shi, Xiaonan; Sun, Wan; Zhao, Jinghui; Liu, Liying; Zhu, Bolin] Tianjin Normal Univ, Coll Chem, Tianjin Key Lab Struct & Peiformance Funct Mol, Tianjin 300387, Peoples R China; [Zhu, Yan-Ping] Collaborat Innovat Ctr Adv Drug Delivery Syst & B, Sch Pharm, Key Lab Mol Pharmacol & Drug Evaluat, Minist Educ, Yantai 264005, Shandong, Peoples R China in 2020, Cited 56. The Name is 2-Chloro-6-methylaniline. Through research, I have a further understanding and discovery of 87-63-8. SDS of cas: 87-63-8

Here we report a protocol to synthesize diversiform fluorinated isocryptolepine analogues with potential biological activities in one step via directed C-2 and C-3 dual C-H functionalization of indoles. We also attempted to take into account fluorinated imidoyl chlorides as a novel kind of synthons in the directed C-H functionalization reactions. As a result, a variety of fluorinated isocryptolepine analogues were obtained in up to 96% yield. Moreover, we conducted control experiments to disclose the reaction mechanism.

Welcome to talk about 87-63-8, If you have any questions, you can contact Chen, C; Wang, YB; Shi, XN; Sun, W; Zhao, JH; Zhu, YP; Liu, LY; Zhu, BL or send Email.. SDS of cas: 87-63-8

Reference:
Patent; ASTRAZENECA AB; NPS PHARMACEUTICALS, INC.; WO2006/20879; (2006); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Recently I am researching about PALLADIUM-CATALYZED CARBOXYLATION; GRIGNARD-REAGENTS; BENZYL CHLORIDES; HALIDES; TRANSFORMATION; COMPLEXES; INSERTION; ALKENES; ESTERS, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [91645120, 21871163, 21911530097]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Hang, W; Yi, YP; Xi, CJ. The CAS is 95-49-8. Through research, I have a further understanding and discovery of 1-Chloro-2-methylbenzene. Application In Synthesis of 1-Chloro-2-methylbenzene

Cp2TiCl2-catalyzed carboxylation of aryl chlorides with carbon dioxide to afford benzoic acids in good yields has been achieved in the presence of n-BuMgCl. The reaction proceeds by a sequential magnesium halide exchange reaction and carboxylation with CO2 in a wide variety of aryl chlorides under mild conditions.

Application In Synthesis of 1-Chloro-2-methylbenzene. Welcome to talk about 95-49-8, If you have any questions, you can contact Hang, W; Yi, YP; Xi, CJ or send Email.

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Recently I am researching about C-H AMINATION; N BOND FORMATION; OXIDATIVE SYNTHESIS; COUPLING REACTIONS; QUINAZOLINONES; METAL; HETEROCYCLES; DERIVATIVES; HYDROGEN; ARYL, Saw an article supported by the . Application In Synthesis of 2,6-Dichlorobenzoic acid. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Hu, FP; Cui, XF; Ban, ZH; Lu, GP; Luo, N; Huang, GS. The CAS is 50-30-6. Through research, I have a further understanding and discovery of 2,6-Dichlorobenzoic acid

Quinazolinones have broad applications in the biological, pharmaceutical and material fields. Studies on the synthesis of these compounds are therefore widely conducted. Herein, a novel and highly efficient copper-mediated tandem C(sp(2))-H amination and annulation of benzamides and amidines for the synthesis of quinazolin-4(1H)-ones is proposed. This synthetic route can be useful for the construction of quinazolin-4(1H)-one frameworks.

Welcome to talk about 50-30-6, If you have any questions, you can contact Hu, FP; Cui, XF; Ban, ZH; Lu, GP; Luo, N; Huang, GS or send Email.. Application In Synthesis of 2,6-Dichlorobenzoic acid

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

An article Cobalt-catalyzed carboxylation of aryl and vinyl chlorides with CO2 WOS:000591568400016 published article about CONJUGATE ADDITION; CARBON-DIOXIDE; HALIDES; BROMIDES; PALLADIUM; SYSTEM in [Wang, Yanwei; Jiang, Xiaomei; Wang, Baiquan] Nankai Univ, Coll Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China; [Wang, Baiquan] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China in 2020, Cited 45. Name: 1-Chloro-2-methylbenzene. The Name is 1-Chloro-2-methylbenzene. Through research, I have a further understanding and discovery of 95-49-8

The transition-metal-catalyzed carboxylation of aryl and vinyl chlorides with CO2 is rarely studied, and has been achieved only with a Ni catalyst or combination of palladium and photoredox. In this work, the cobalt-catalyzed carboxylation of aryl and vinyl chlorides and bromides with CO2 has been developed. These transformations proceed under mild conditions and exhibit a broad substrate scope, affording the corresponding carboxylic acids in good to high yields.

Name: 1-Chloro-2-methylbenzene. Welcome to talk about 95-49-8, If you have any questions, you can contact Wang, YW; Jiang, XM; Wang, BQ or send Email.

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

An article Palladium-Catalyzed Amidation and Amination of (Hetero)aryl Chlorides under Homogeneous Conditions Enabled by a Soluble DBU/NaTFA Dual-Base System WOS:000481979500007 published article about CROSS-COUPLING REACTIONS; FUNCTIONAL-GROUP COMPATIBILITY; LARGE-SCALE SYNTHESIS; LONG-LIVED CATALYSTS; ONE-POT SYNTHESIS; C-N; OXIDATIVE ADDITION; ALPHA-CARBOLINES; ARYL AMINATION; SCOPE in [Beutner, Gregory L.; Coombs, John R.; Green, Rebecca A.; Inankur, Bahar; Lin, Dong; Qiu, Jun; Roberts, Frederick; Simmons, Eric M.; Wisniewski, Steven R.] Bristol Myers Squibb Co, Chem & Synthet Dev, One Squibb Dr, New Brunswick, NJ 08903 USA in 2019.0, Cited 69.0. Quality Control of 1-Chloro-2-methylbenzene. The Name is 1-Chloro-2-methylbenzene. Through research, I have a further understanding and discovery of 95-49-8

The palladium-catalyzed coupling of aryl and heteroaryl chlorides with primary amides under mild homogeneous reaction conditions is reported. Successful C-N coupling is enabled by the use of a unique dual-base system consisting of DBU and NaTFA, which serve as proton acceptor and halide scavenger, respectively, using low catalyst loadings (0.5 mol %) with readily available, air-stable palladium precatalysts. The DBU/NaTFA system also enables the room-temperature coupling of primary aryl amines with aryl chlorides and is tolerant of a variety of base-sensitive functional groups.

Welcome to talk about 95-49-8, If you have any questions, you can contact Beutner, GL; Coombs, JR; Green, RA; Inankur, B; Lin, D; Qiu, J; Roberts, F; Simmons, EM; Wisniewski, SR or send Email.. Quality Control of 1-Chloro-2-methylbenzene

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics