Month: November 2021

In 2020 CATAL LETT published article about METAL-ORGANIC FRAMEWORKS; AEROBIC OXIDATION; CYCLOHEXANE OXIDATION; GREEN CHEMISTRY; TOLUENE; EFFICIENT; PERFORMANCE; PORPHYRINS; MANGANESE; COMPLEX in [Shen, Hai-Min; Qi, Bei; Hu, Meng-Yun; Liu, Lei; Ye, Hong-Liang; She, Yuan-Bin] Zhejiang Univ Technol, Coll Chem Engn, State Key Lab Breeding Base Green Chem Synth Tech, Hangzhou 310014, Peoples R China in 2020, Cited 75. The Name is 1-Chloro-2-methylbenzene. Through research, I have a further understanding and discovery of 95-49-8. SDS of cas: 95-49-8

A protocol for solvent-free and additive-free oxidation of primary benzylic C-H bonds with O(2)was presented through adjusting the combination of metalloporphyrins and NHPI as binary catalysts to overcome the deficiencies encountered in current oxidation systems. The effects of reaction temperature, porphyrin structure, central metal, catalyst loading and O(2)pressure were investigated systematically. For the optimized combination of T(2-OCH3)PPCo and NHPI, all the primary benzylic C-H bonds could be functionalized efficiently and selectively at 120 degrees C and 1.0 MPa O(2)with aromatic acids as the primary products. The selectivity towards aromatic acids could reach up to 70-95% in the conversion of more than 30% for most of the substrates possessing primary benzylic C-H bonds in the metalloporphyrin loading of 0.012% (mol/mol). And the superior performance of T(2-OCH3)PPCo among the metalloporphyrins investigated was mainly attributed to its high efficiency in charge transfer and fewer positive charges around central metal Co (II) which favored the adduction of O-2 to cobalt (II) forming the high-valence metal-oxo complex followed by the production of phthalimide N-oxyl radical (PINO) and the initiation of the catalytic oxidation cycle. This work would provide not only an efficient protocol in utilization of hydrocarbons containing primary benzylic C-H bonds, but also a significant reference in the construction of more efficient C-H bonds oxidation systems Graphic Abstract The solvent-free and additive-free oxidation of primary benzylic C-H bonds with O(2)was presented through adjusting the combination of metalloporphyrins and NHPI as binary catalysts, and the highest selectivity towards aromatic acid reached up to 95.1% with the conversion of 88.5% in the optimized combination of T(2-OCH3)PPCo and NHPI. [GRAPHICS] .

Bye, fridends, I hope you can learn more about C7H7Cl, If you have any questions, you can browse other blog as well. See you lster.. SDS of cas: 95-49-8

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

In 2020.0 APPL ORGANOMET CHEM published article about ONE-POT SYNTHESIS; REUSABLE CATALYST; CUI NANOPARTICLES; PALLADIUM NANOPARTICLES; SULFONAMIDE DERIVATIVES; HIGHLY EFFICIENT; ARYL BROMIDES; MILD; ARYLATION; HALIDES in [Alavinia, Sedigheh; Ghorbani-Vaghei, Ramin; Arabian, Iman Ali] Bu Ali Sina Univ, Fac Chem, Dept Organ Chem, Hamadan 65174, Hamadan, Iran; [Rakhtshah, Jamshid] Univ Tabriz, Fac Chem, Dept Inorgan Chem, Tabriz, Iran; [Seyf, Jaber Yousefi] Univ Technol, Dept Chem Engn, Hamadan, Hamadan, Iran in 2020.0, Cited 58.0. The Name is 2,6-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-30-6. Recommanded Product: 50-30-6

A porous cross-linked poly (ethyleneamine)-polysulfonamide (PEA-PSA) as a novel organic support system is synthesized in the presence of silica template by nanocasting technique. The paper demonstrates immobilization of CuI nanoparticles inside the pores (PEA-PSA@CuI) for the facile recovery and recycling of these nanoparticles. The presence of porous PEA-PSA and PEA-PSA@CuI nanocomposites was confirmed using FT-IR spectroscopy, FE-SEM, EDX, TGA, XRD, TEM, BET, XPS, WDX, H-1 NMR, and ICP-OES techniques. The PEA-PSA@CuI along with Ag(I)/K2S2O8 was implemented as a reusable cooperative catalyst-oxidant system in the N-arylation of p-toluenesulfonamide with substituted carboxylic acids in mild condition. So, the novel decarboxylative cross-coupling catalyzed by copper and silver has been developed. Aromatic, secondary and tertiary aliphatic acids underwent high efficient decarboxylative processes with p-toluenesulfonamide to afford the corresponding products. This method provides a practical approach for the flexible synthesis of sulfonamides from the readily affordable substrates. The catalyst is highly reusable and efficient, especially in terms of time and yield of the desired product.

Bye, fridends, I hope you can learn more about C7H4Cl2O2, If you have any questions, you can browse other blog as well. See you lster.. Recommanded Product: 50-30-6

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Recently I am researching about VISIBLE-LIGHT PHOTOREDOX; DIRECT ARYLATION; METAL-COMPLEXES; ANION-RADICALS; REDUCTION; HALIDES; BOND; FUNCTIONALIZATION; ACTIVATION; DRIVEN, Saw an article supported by the Office of the Vice Chancellor for Research and Graduate Education at the University of Wisconsin Madison; Wisconsin Alumni Research Foundation; NSFNational Science Foundation (NSF) [CHE-1048642]; NIHUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USA [IS10 OD020022-1]. SDS of cas: 95-49-8. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Cowper, NGW; Chernowsky, CP; Williams, OP; Wickens, ZK. The CAS is 95-49-8. Through research, I have a further understanding and discovery of 1-Chloro-2-methylbenzene

We describe a new catalytic strategy to transcend the energetic limitations of visible light by electrochemically priming a photocatalyst prior to excitation. This new catalytic system is able to productively engage aryl chlorides with reduction potentials hundreds of millivolts beyond the potential of Na-0 in productive radical coupling reactions. The aryl radicals produced via this strategy can be leveraged for both carbon-carbon and carbon-heteroatom bond-forming reactions. Through direct comparison, we illustrate the reactivity and selectivity advantages of this approach relative to electrolysis and photoredox catalysis.

Welcome to talk about 95-49-8, If you have any questions, you can contact Cowper, NGW; Chernowsky, CP; Williams, OP; Wickens, ZK or send Email.. SDS of cas: 95-49-8

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Authors Zhang, Z; Cordier, M; Dixneuf, PH; Soule, JF in AMER CHEMICAL SOC published article about PALLADIUM-CATALYZED AMINATION; RAPID CONSTRUCTION; LIGANDS; ARYL; COMPLEXES; ARYLATION in [Zhang, Zhuan; Cordier, Marie; Dixneuf, Pierre H.; Soule, Jean-Francois] Univ Rennes, CNRS, ISCR UMR 6226, F-35000 Rennes, France in 2020.0, Cited 33.0. Category: chlorides-buliding-blocks. The Name is 1-Chloro-2-methylbenzene. Through research, I have a further understanding and discovery of 95-49-8

We report herein P(III)-directed C-H bond alkenylation of (dialkyl)- and (diaryl)biarylphosphines using internal alkynes. Chloride-free [Rh(OAc)(COD)](2) acts as a better catalyst than commercially available [RhCl(COD)](2). Conditions were developed to control the mono- and difunctionalization depending on the alkyne stoichiometry. One of these novel bisalkenylated (dialkyl)biarylphosphines was employed for the preparation of a palladium(II) complex, and some of these functionalized ligands outperformed their corresponding unfunctionalized phosphines in Pd-catalyzed amidation with sterically hindered aryl chlorides.

Welcome to talk about 95-49-8, If you have any questions, you can contact Zhang, Z; Cordier, M; Dixneuf, PH; Soule, JF or send Email.. Category: chlorides-buliding-blocks

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article A Practical Synthesis of 3-Functionalized Coumarins fromo-Cresols and Active Methylene Compounds under Metal and Catalyst-Free Conditions Usingtert-Butyl Hydrogen Peroxide published in 2020.0. Computed Properties of C7H7Cl, Reprint Addresses Srivastava, V (corresponding author), Indian Inst Technol BHU, Dept Chem, Varanasi 221005, Uttar Pradesh, India.. The CAS is 95-49-8. Through research, I have a further understanding and discovery of 1-Chloro-2-methylbenzene

An efficient synthesis of 3-functionalized coumarins is demonstrated fromo-cresols and active methylene compounds under solvent-, metal- and catalyst-free conditions in the presence of 70 % aqueoustert-butyl hydrogen peroxide. The important features of this protocol are operational simplicity, mild reaction conditions and good to excellent yield of the products.

Computed Properties of C7H7Cl. Bye, fridends, I hope you can learn more about C7H7Cl, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

An article Design and Synthesis of Novel Positive Allosteric Modulators of alpha 7 Nicotinic Acetylcholine Receptors with the Ability To Rescue Auditory Gating Deficit in Mice WOS:000455561400010 published article about VITRO PHARMACOLOGICAL CHARACTERIZATION; RELEASE; AGONIST; SCHIZOPHRENIA; DISCOVERY; TARGETS; SERIES; ACID in [Li, Yuanheng; Jiao, Wenxuan; Huang, Zongze; Meng, Ying; Luo, Laichun; Wang, KeWei; Sun, Qi] Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China; [Sun, Lilan; Zhang, Fang; Wang, KeWei] Qingdao Univ, Sch Pharm, Dept Pharmacol, Qingdao 266021, Peoples R China; [Yang, Taoyi; Tang, Jingshu; Huang, Xiaomin; Wang, Xintong; Bian, Xiling; Wang, KeWei] Peking Univ, Sch Pharmaceut Sci, Dept Mol & Cellular Pharmacol, Beijing 100191, Peoples R China in 2019, Cited 49. The Name is 2-Chloro-6-methylaniline. Through research, I have a further understanding and discovery of 87-63-8. Name: 2-Chloro-6-methylaniline

A series of novel thiazolo[4,5-d]pyrimidin-7(6H)-ones (3aa-3eq) were designed, synthesized, and evaluated as the type I positive allosteric modulators of human alpha 7 nAChR expressed in Xenopus ooctyes by a two-electrode voltage clamp. The structure-activity relationship analysis identified the compound 3ea as a potent and efficacious PAM with the maximum activation effect of the alpha 7 current of over 1633% in the presence of acetylcholine (100 mu M) and an EC50 = 1.26 mu M. It is highly specific to alpha 7 nAChR over other subtypes of nAChR, 5-HT3A, NMDA, and GABA(A) receptors. Compound 3ea showed an elimination half-life of 10.8 +/- 1.5 h for 3 mg/kg, i.v., and 7.4 +/- 1.1 h for 60 mg/kg, i.g. in rat. It also exhibited sufficient blood-brain barrier penetration with no significant effect on hERG channel. Most importantly, compound 3ea dose-dependently (0.1-1 mg/kg, i.p.) reversed the prepulse inhibition deficit induced by MK-801 in the mouse schizophrenia model. X

Name: 2-Chloro-6-methylaniline. Welcome to talk about 87-63-8, If you have any questions, you can contact Li, YH; Sun, LL; Yang, TY; Jiao, WX; Tang, JS; Huang, XM; Huang, ZZ; Meng, Y; Luo, LC; Wang, XT; Bian, XL; Zhang, F; Wang, KW; Sun, Q or send Email.

Reference:
Patent; ASTRAZENECA AB; NPS PHARMACEUTICALS, INC.; WO2006/20879; (2006); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

An article High photocatalytic activity of a NiO nanodot-decorated Pd/SiC catalyst for the Suzuki-Miyaura cross-coupling of aryl bromides and chlorides in air under visible light WOS:000566793700008 published article about GENERAL-METHOD; PALLADIUM; NANOPARTICLES; NHC; BORYLATION; ACTIVATION; PHOTOREDOX; OXIDATION; BIARYLS; HALIDES in [Jiao, Zhi-Feng; Guo, Xiang-Yun] Changzhou Univ, Sch Petrochem Engn, Jiangsu Key Lab Adv Catalyt Mat & Technol, Changzhou 213164, Peoples R China; [Tian, Ya-Ming; Radius, Udo; Braunschweig, Holger; Marder, Todd B.; Guo, Xiao-Ning] Julius Maximilians Univ Wurzburg, Inst Anorgan Chem, D-97074 Wurzburg, Germany; [Tian, Ya-Ming; Radius, Udo; Braunschweig, Holger; Marder, Todd B.; Guo, Xiao-Ning] Julius Maximilians Univ Wurzburg, Inst Sustainable Chem & Catalysis Boron, D-97074 Wurzburg, Germany; [Jiao, Zhi-Feng; Zhang, Bin; Qiao, Yan; Wang, Ying-Xiong; Qin, Yong; Guo, Xiang-Yun] Chinese Acad Sci, Inst Coal Chem, State Key Lab Coal Convers, Taiyuan 030001, Peoples R China; [Hao, Cai-Hong] North Univ China, Sch Energy & Power Engn, Taiyuan 030051, Peoples R China; [Hao, Cai-Hong] North Univ China, Sch Mat Sci & Engn, Taiyuan 030051, Peoples R China in 2020.0, Cited 79.0. Category: chlorides-buliding-blocks. The Name is 1-Chloro-2-methylbenzene. Through research, I have a further understanding and discovery of 95-49-8

The Suzuki-Miyaura cross-coupling reaction is an effective process for C-C bond formation in organic synthesis. Herein, we report a NiO nanodot-decorated Pd/SiC catalyst, synthesized by atomic layer deposition, which shows high photocatalytic activity for the Suzuki-Miyaura coupling of both aryl bromides and chlorides with phenylboronic acid at 30 degrees C in air. The Mott-Schottky contact in SiC/Pd enhances the rapid transfer of the photogenerated electrons from SiC to Pd nanoparticles. Moreover, the energy different between the highest occupied molecular orbital of the ultrafine NiO nanodots and the Fermi level of Pd forces a spontaneous electron transfer from NiO to Pd. As a result, the concentrated electrons in the Pd nanoparticles can facilitate the cleavage of C-Br or C-Cl bonds, which normally requires rather high temperatures in thermal processes. The holes left on the SiC support can assist the cleavage of the C-B bond. (C) 2020 Elsevier Inc. All rights reserved.

Category: chlorides-buliding-blocks. About 1-Chloro-2-methylbenzene, If you have any questions, you can contact Jiao, ZF; Tian, YM; Zhang, B; Hao, CH; Qiao, Y; Wang, YX; Qin, Y; Radius, U; Braunschweig, H; Marder, TB; Guo, XN; Guo, XY or concate me.

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Zheng, XJ; Li, CS; Cui, MY; Song, ZW; Bai, XQ; Liang, CW; Wang, HY; Zhang, TY in [Zheng, Xian-Jing; Song, Ze-Wen; Bai, Xue-Qian; Liang, Cheng-Wu; Wang, Hui-Yan; Zhang, Tian-Yi] Jilin Med Univ, Jilin 132013, Jilin, Peoples R China; [Li, Chun-Shi; Cui, Ming-Yue] Third Peoples Hosp Dalian, Dalian 116000, Liaoning, Peoples R China; [Zheng, Xian-Jing; Song, Ze-Wen] Yanbian Univ, Dept Pharm, Yanji 133002, Jilin, Peoples R China published Synthesis, biological evaluation of benzothiazole derivatives bearing a 1,3,4-oxadiazole moiety as potential anti-oxidant and anti-inflammatory agents in 2020, Cited 26. Recommanded Product: 2,4-Dichlorobenzoic acid. The Name is 2,4-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-84-0.

Twenty benzothiazole derivatives bearing a 1,3,4-oxadiazole moiety were synthesized and evaluated for their anti-oxidant and anti-inflammatory activities. Among these compounds, 8h and 81 were appeared to have high radical scavenging efficacies as 0.05 +/- 0.02 and 0.07 +/- 0.03 mmol/L of IC50, values in ABTS(+center dot) bioassay, respectively. In anti-inflammatory tests, compound 8h displayed good activity with 57.35% inhibition after intraperitoneal administration, which was more potent than the reference drug (indomethacin). Molecular modeling studies were performed to investigate the binding mode of the representative compound 8h into COX-2 enzyme. In vitro enzyme study implied that compound 8h exerted its anti-inflammatory activity through COX-2 inhibition.

Recommanded Product: 2,4-Dichlorobenzoic acid. Bye, fridends, I hope you can learn more about C7H4Cl2O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Recently I am researching about SELECTIVE HYDROGENATION; PRIMARY AMINES; NITRILES; ALDEHYDES; KETONES; IMINES, Saw an article supported by the CONACYTConsejo Nacional de Ciencia y Tecnologia (CONACyT) [A1-S-7657, 629543]; DGAPA-UNAMUniversidad Nacional Autonoma de Mexico [IN-200129]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Rodriguez, AA; Garduno, JA; Garcia, JJ. The CAS is 95-49-8. Through research, I have a further understanding and discovery of 1-Chloro-2-methylbenzene. Category: chlorides-buliding-blocks

The use of the nickel(ii) complex [(TEEDA)NiCl2] (1; TEEDA= N,N,N ‘,N ‘-tetraethyl-ethylendiamine) and nickel(0) complex [Ni(COD)(2)] (5) as pre-catalysts in the additive-free catalytic hydrogenation of benzonitrile (BN) is reported. In the presence of 1 (1 mol%), BN was hydrogenated under relatively mild reaction conditions (100 degrees C, 120 psi H-2, 72 h) to the corresponding secondary imine, N-benzylidenebenzylamine (BBA), in very good yield (83%). As a counterpart, 5 (1 mol%) selectively hydrogenated BN to benzylamine (BA) in excellent yield (96%) under similar reaction conditions (80 degrees C, 120 psi H-2, 24 h). In both cases, nickel nanoparticles (Ni-NPs) were identified as the catalytically active species. These Ni-NPs were formed in situ from 1 and 5 without external additives or additional stabilizers. The use of complex 5 was extended to the hydrogenation of different (hetero) aromatic and aliphatic nitriles.

Bye, fridends, I hope you can learn more about C7H7Cl, If you have any questions, you can browse other blog as well. See you lster.. Category: chlorides-buliding-blocks

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Authors Zhang, P; Zhao, XM in CHINESE JOURNAL STRUCTURAL CHEMISTRY published article about MESENCHYMAL STEM-CELLS; ADIPOSE-TISSUE; DENTAL-PULP; REGENERATION in [Zhang Peng; Zhao Xiao-Mei] Shaanxi Univ Chinese Med, Sch Pharm, Xianyang 712046, Shaanxi, Peoples R China in 2020, Cited 15. Category: chlorides-buliding-blocks. The Name is 2-Chloro-6-methylaniline. Through research, I have a further understanding and discovery of 87-63-8

The heterocyclic compound 2-amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide (1), designed using 2-chloro-6-methylaniline (2) as the start material, was successfully obtained via multiple synthesis route and finally characterized by IR, H-1 NMR, and single-cystal X-ray crystallography. To select the suitable candidates for tissue regeneration, the induction activity of the compound on the dental pulp mesenchymal stem cells (DP-MSCs) was evaluated. Firstly, the DP-MSCs cells were isolated and the cell colon formation ability was measured after compound treatment with cell colony determination. After that, the RT-PCT assay was conducted and the relative expression level of the genes related with cell osteogenesis and proliferation was further detected.

Welcome to talk about 87-63-8, If you have any questions, you can contact Zhang, P; Zhao, XM or send Email.. Category: chlorides-buliding-blocks

Reference:
Patent; ASTRAZENECA AB; NPS PHARMACEUTICALS, INC.; WO2006/20879; (2006); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics