I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article Online clean-up setup for the determination of non-fluorescent acidic pharmaceutical drugs in complex biological samples published in 2019. Recommanded Product: 2,4-Dichlorobenzoic acid, Reprint Addresses Muhammad, N (corresponding author), Wuchang Univ Technol, Dept Environm Engn, Wuhan, Hubei, Peoples R China.; Muhammad, N; Guo, DD (corresponding author), Zhejiang Univ, Dept Chem, Xixi Campus, Hangzhou 310028, Zhejiang, Peoples R China.; Guo, DD (corresponding author), Ningbo Univ, Inst Drug Discovery Technol, Ningbo 315211, Zhejiang, Peoples R China.. The CAS is 50-84-0. Through research, I have a further understanding and discovery of 2,4-Dichlorobenzoic acid
Analysis of acidic pharmaceuticals in complex biological samples is a challenging and formidable task due to the existence of interfering constituents within the sample matrices. Therefore, in order to avoid analytical column clogging and suppression/enhancement of signals of the analyte of interest, herein a simple, cost-effective and quick online ion chromatography based clean-up setup was introduced. This system was further coupled with a cost-effective homemade photochemically induced fluorimetric (PIF) setup for direct online conversion of non fluorescent acidic pharmaceutical drugs into their respective fluorescent species. This advantageous system was favorably applied for the determination of four non-fluorescent acidic compounds in two complex biological samples (human serum and oral fluid) with minimum labor and organic solvent consumption. At optimized conditions, the developed method has shown good sensitivity, selectivity, satisfactory recoveries (88.68-102.14%) and low limits of detection (0.35-8.10 mu g/L) with minimum or zero matrix effect.
Recommanded Product: 2,4-Dichlorobenzoic acid. About 2,4-Dichlorobenzoic acid, If you have any questions, you can contact Muhammad, N; Guo, DD; Zhang, Y; Intisar, A; Subhani, Q; Qadir, MA; Cui, HR or concate me.
Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics