Application of 27139-97-5, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 27139-97-5, name is 2-Bromo-4-chloro-1-methylbenzene, This compound has unique chemical properties. The synthetic route is as follows.
To a reaction vessel purged with nitrogen were charged 45 g of 2-bromo-4-chlorotoluene, 36.6 g of carbazole, 7.0 g of a copper powder, 90.8 g of potassium carbonate, 4.7 ml of dimethyl sulfoxide, and 25 ml of dodecylbenzene, followed by heating, and stirred at 200°C for 44 hours. After cooling to 80°C, thereto was added 400 ml of toluene, an insoluble matter was removed by filtration therefrom, and vacuum concentration was conducted to obtain a crude product. Hexane was added to the crude product to precipitate the crude product. It was collected by filtration and then purified by column chromatography (carrier: silica gel, eluent: hexane) to obtain 20.3 g (yield: 32percent) of 9-(3-chloro-6-methylphenyl)-9H-carbazole as a white powder.
The chemical industry reduces the impact on the environment during synthesis 2-Bromo-4-chloro-1-methylbenzene. I believe this compound will play a more active role in future production and life.
Reference:
Patent; Hodogaya Chemical Co., Ltd.; Shinshu University; YOKOYAMA Norimasa; KABASAWA Naoaki; ICHIKAWA Musubu; OTSURU Sohei; EP2679587; (2014); A1;,
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