Adding a certain compound to certain chemical reactions, such as: 112-26-5, name is 1,2-Bis(2-chloroethoxy)ethane, belongs to chlorides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 112-26-5, category: chlorides-buliding-blocks
7.7Ig (50 mmo 1) of 2,6-dimethoxyphenol and 8.42 g (45 mmol) of 1,2- (dichloroethane) ethane were added to IOOml of acetonitrile at a temperature of 20 C with stirring , 6.06 g (108 mmol) of potassium hydroxide was added thereto, and the temperature was raised to 82 C. After 92 hours of reaction, acetonitrile was distilled off at atmospheric pressure to obtain orange turbid liquid.[0027] IOOml dichloromethane was added to the above-mentioned orange turbid liquid 1, the insoluble matter was filtered off, washed twice with 50 ml of IM sodium hydroxide solution and twice with saturated sodium chloride solution (20 C) Dried over anhydrous magnesium sulfate and evaporated to dryness at atmospheric pressure to give a yellow oily liquid 2;[0028] To the above yellow oily liquid 3 was added 25 ml of diethyl ether, the temperature was raised to 35 C, the insoluble matter was filtered off, cooled to _15 C, cooled for 3 hours, the liquid was stratified, and the pale yellow solution was taken and cooled to -15 C (2- (2,6-dimethoxyphenoxy) ethoxy) ethane in a yield of 69.33% and a purity of 98.42% as a white powder
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,2-Bis(2-chloroethoxy)ethane, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Xi’an Modern Chemical Institute; Lu Tingting; Ji Yueping; Zhang Lijie; Liu Yajing; Wang Wei; Pan Yongfei; Xu Minghui; Mo Hongchang; Lu Xianming; Ding Feng; (6 pag.)CN106946664; (2017); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics